Red Ginger (Zingiber officinale var. Amarum) Infusion Increases Concentration of Luteinizing Hormone and Testosterone in Male Rats
Journal Title: SAINS MEDIKA (Journal of Medicine and Health) - Year 2016, Vol 7, Issue 2
Abstract
Introduction: Herbal remedies have been developed as a complementary therapy to increase sex hormones. The administration of the ethanolic extract of red ginger (Zingiber officinale var. Amarum) has been shown to increase spermatogenic cells, motility and morphology of sperm in mice. However, the effect of red ginger infusion on the level of testosterone and luteinizing hormone (LH) has not been done. Objective: to examine the effect of red ginger infusion on LH and testosterone levels of male Wistar rats. Methods: The study was designed as an experimental post-test only control group design. Twenty four male Wistar rats of 200-250 g body weight aged + 3-4 months were divided into four groups. a control group (G-1) was given distilled water 2 ml/day. Group 2 (G-2), Group 3 (G-3), and group 4 (G-4) were treated with 10%, 20%, and 40% infusion by dissolving 2 ml of ginger in distilled water. On day 15, blood samples were taken and assayed for LH and testosterone. Results: The one-way ANOVA test showed difference in levels of LH and testosterone between groups (p <0.001). Post Hoc LSD test results showed that the levels of LH of G-1 (0350) was significantly lower than that of G-2 (1082), G-3 (1 253), and G-4 (0923), p <0.005. While the levels of testosterone in the G-1 (0.2718) significantly lower than the G-2 (0.7797), G-3 (0.8285), and the G-4 (0.9142) (p <0.005). Conclusion: red ginger infusion for 14 days can increase the levels of LH and testosterone in male rats.
Authors and Affiliations
Alida Nihayah, Taufiqurrachman Nasihun, Isradji Israhnanto
Keywords
Related Articles
- EP ID EP219990
- DOI -
- Views 96
- Downloads 0
Customer’s Perspective in Performance Assessment of Pharmacy Instillation of RSUD X with Balanced Scorecard
Balanced Scorecard performance measurement (financial perspective, customer perspective, internal business perspective, and learning and growth perspective) offers a more thorough and comprehensive evaluation in a public...
Effect of Tempe Flour Supplementation During Pregnancy on Blood Sugar and Lipid Profile Study on Wistar Rats which Gets Restricted Diet during Pregnancy
Background: Low birth weight (<2500 grams) is representation of a nutritional deficiency during pregnancy, this condition is associated with increased incidence of degenerative diseases. Tempe as traditional Indonesian f...
The Correlation of Exercise and Range of Motion (ROM) on Elderly Knee Observasional Study on Elderly People in Pedurungan Semarang
Background: In aging process, decreasing of musculosceletal capabilities will reduce physical activity and excercise, as well as Range Of Motion (ROM). In order to maintain the normality of ROM, joints and muscles should...
Scope of Visum Et Repertum as a Legal Mean of Proof in Crime Related to Human Body in Rumah Sakit Bhayangkara Semarang
Visum et repertum (VER) is part of forensic and medico-legal science. VER is a written report by a sworn doctor and has the authority of what he/she has seen and and found in the evidence presented and conclude the evalu...
Risk Factor Associated with Hepatitis B Incidence in Pondok Pesantren Putri Ibnul Qoyyim Yogyakarta
Hepatitis B virus has been a problem in developing countries. The transmission of HBV is through the exposure to the blood or secret of the infected patients. Woman has 3 times higher risk to get HBV than men. The plemin...