Reduced antioxidant status for prolonged period due to repeated stress exposure in rat
Journal Title: Журнал ÑтреÑÑ-физиологии и биохимии - Year 2011, Vol 7, Issue 2
Abstract
The objective of the study was to find out whether or not exposure to a stressor after an initial stressful experience augments stress response. Antioxidant status was determined by measuring changes in the activities of the hepatic free radical scavenging enzymes viz, superoxide dismutase (SOD), glutathione-S-transferase (GST), glucose-6-phosphate-dehydrogenase (G6PDH) and catalase (CAT) and levels of hepatic malondialdehyde (MDA) following exposure to 1 h restraint (RS) and after a gap of 4 h to forced swimming exercise (FS) in rats. The activities of hepatic CAT, SOD, G6PDH and GST were significantly reduced 2 h after RS compared to controls and 4 h after FS the activities of CAT and G6PDH remained at lower levels i.e. they were similar to those found after RS , whereas SOD and GST showed further significant decrease compared to those found after RS. On the other hand the MDA levels, indicative of lipid peroxidation were significantly increased after RS and showed further significant increase after FS. The results reveal that after initial stressful experience, the stress response is augmented due to exposure to another stressor whereas the system does not get habituated to stress exposure.
Authors and Affiliations
M. Devaki, R. Nirupama, H. Yajurvedi
Keywords
Related Articles
- EP ID EP102770
- DOI -
- Views 88
- Downloads 0
24-Epibrassinolide Mediated Changes in Photosynthetic pigments and Antioxidative Defence System of Radish Seedlings under Cadmium and Mercury Stress
The present work was conducted to study the effects of 24-EBL on photosynthetic pigments (total chlorophyll, chl a, chl b, carotenoid, anthocyanin and flavonoid content) and activities of antioxidative enzymes (guaiacol...
Effect of chelating agents and metal ions on nickel bioavailability and chlorophyll fluorescence response in wheat- An approach for attenuation of Ni stress
The objectives of the study are to analyze the physiological changes, biochemical alterations and attenuation of nickel toxicity effects in wheat seedlings under combined applications of Ni ions, metal chelators (EDTA/Ci...
Evaluation of Oxidative Stress in Sheep Affected with Peste des petits ruminants
The aim of the investigation was to evaluate oxidative stress in sheep affected with peste des petits ruminants (PPR). Oxidative stress in the affected sheep was evaluated by determining various serum biomarkers viz. vi...
INDUCTION OF ANAEROBIC PROCESSES IN BAIKAL ENDEMICS EULIMNOGAMMARUS VITTATUS (DYB.) AND E. VERRUCOSUS (DYB.) (AMPHIPODA, CRUSTACEA)
The data confirming the ability of Baikalian endemic species Eulimnogammarus vittatus (Dyb.) and E. verrucosus (Dyb.) to activate anaerobic glycolysis under hypoxia are presented. The differences in the degree and the ra...
The Exogenous Amelioration Roles of Growth Regulators on Crop Plants Grow under Different Osmotic Potential
The production of fresh and dry matter of maize, wheat, cotton, broad and parsley plants show a variable response to the elevation of salinity stress. The production of fresh and dry matter of shoots and roots in wheat a...