Reference interval of serum bilirubin panel in healthy individuals of attending tertiary care hospital - a cross sectional study
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2017, Vol 4, Issue 1
Abstract
Introduction: Reference Intervals are the most common decision making tools for interpretation of various biochemical reports. Age, sex, ethnicity, diet, physical and socio-economic conditions, affect the physiology of population. Hence it is necessary to setup reference values that are applicable to specific population rather than to borrow them from other population based studies or from literature from reagent kit manufacturers. So we intend to establish the reference intervals of serum bilirubin profile in southern coastal Karnataka population. Methodology: Hospital based cross sectional study was done involving 200 subjects. The subjects were randomly selected from the population, which included medical students, health professionals, and those who attended different OPDs and health camps organized by the K S Hegde hospital for general check-ups under health plan scheme. Total bilirubin and direct bilirubin was estimated by dichlorodiphenyl diazonium method. Indirect bilirubin (Total bilirubin-Direct bilirubin) was calculated. Results: The reference intervals observed for men and women are as follows: Total bilirubin (0.1-1.3)mg/dl and (0.1-1.38)mg/dl, serum direct bilirubin (0-0.5)mg/dl and (0-0.3)g/dl, and serum indirect bilirubin (0.1-0.9)mg/dl and (0.1-1.3)mg/dl respectively. With the advancement of age, a difference in the reference interval was observed among both the sex. Conclusion: The present study showed a difference in the reference intervals between males and females and also a categorical age wise difference was obtained.
Authors and Affiliations
Shruthi Rai P, Sukanya Shetty, Roopa Bhandary, Ashalatha V Rao
Keywords
Related Articles
- EP ID EP295895
- DOI 10.18231/2394-6377.2017.0017
- Views 58
- Downloads 0
Investigating pre and post-operative blood gases and serum electrolyte in patients undergoing coronary artery bypass surgery (CABG)
Background: Arterial blood gas analysis is a common investigation exercised in emergency room and ICU. In post-operative CABG patients, acid base alterations is the commonest problem encountered. Thus, constant check on...
Gender specific utility of lipid ratios and its correlation with systemic inflammation in acute myocardial infarction (AMI) patients with type 2 diabetes mellitus – A hospital based study
Objective To evaluate Gender specific alterations in the levels of serum lipid profile parameters Total Cholesterol TC Triglycerides TG Low density lipoprotein Cholesterol LDLC High density lipoprotein Cholesterol HDLC n...
A study on role of Oxidative stress and Calcium-Phosphorous Ratio in Rheumatoid Arthritis
Background: Rheumatoid arthritis is one of the chronic inflammatory disease affecting joints and other organs is primarily of an unknown etiology with an incidence of 1% to 2% of total world population.one of the current...
Correlation between Ischemia modified albumin with pH in acidosis and alkalosis: A possible link
Ischemia modified albumin (IMA), a recently developed marker for myocardial ischemia is measured by using albumin cobalt binding (ACB) assay. The correlation between the formation of IMA and alterations in the pH levels...
“Ratio of AST/ALT and serum gamma glutamyl transferase (GGT) activity in chronic alcoholics and acute viral hepatitis”
Background: Liver enzymes AST, ALT, GGT (Gamma Glutamyl Transferase), ALP levels in serum was measured in Chronic alcoholics and acute viral hepatitis and controls. Analysis was done to find out the significance of liver...