Reference models of lung function parameters from FVC maneuver for south Indian male early adolescent population
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2015, Vol 5, Issue 3
Abstract
Background: Usefulness of any test is determined by the availability of suitable standards. Lung function parameters are dependent on multiple anthropometric, genetic, and environm ental factors. Some of these effects can be transient; hence, updating of normative standards for pulmonary function test (P FT) parameters on a regular basis in every ethnically distinct society is of overriding importance. Aims and Objective: To correlate lung function parame ters [obtained from forced vital capacity (FVC) maneuver] with anthropometric variables and age, and to derive normative data for these parameters using the best possible combination of independent variables. Materials and Methods: This is a cross-sectional s tudy of lung function in a non-hospital-based early adolescent male populat ion. It included 91 male children in the age group of 10 – 15 years. Lung function parameters were obtained using a computerized spirometer wi th Fleisch-type pneumotachograph, which were subjected to correlational analysis with height, weight, and age. Regression a nalyses were performed for PFT parameters by introducing age/ anthropometric data as independent variables. Results: All PFT parameters except forced expiratory volume in 1 s (FEV 1 )/FVC showed positive correlation with height, weight and age. Regression analysis yielded that height alone (FEV 1 and MEF25), age alone (MEF50, MEF75, MMEF, and PEF), and age with height (FV C) contributed for the variance in these PFT parameters. Conclusion: A population-, age-, and sex-speci fi c linear prediction equations are presented for various PFT parameters based on the cross-sectional study conducted in an early adolescent male population from south India.
Authors and Affiliations
J. Shivakumar, Jnaneshwara P Shenoy, Sadashiv L Karne, Sunilkumar S Biradar, Ningappa S Muniyappanavar, Gajanan H Nayak
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