Reflux-Related Renal Injury (Reflux Nephropathy): Do Nonsteroidal Anti-Inflammatory Drugs (Ibuprofen) Increases’ the Risks?
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 12
Abstract
Reflux predisposes to facilitating the transport of bacteria from the bladder to the upper urinary tract and infection of the kidney by it. So the objectives of this study were to examine the influence of nonsteroidal anti-inflammatory drugs (Ibuprofen) in risk of reflux nephropathy. In this study we conducted a description of a case series (Children who had febrile UTI and treatment with ibuprofen 193(case group), and acetaminophen180 (control group)) in the pediatric clinic of Amirkabir hospital to characterize risk of Ibuprofen in a cohort study of patients with reflux nephropathy. The prevalence of reflux nephropathy was 4% in control group and 26% in case group. Based on chi-square test, the distribution of reflux nephropathy is difference in the two groups (p=0.0003). We concluded that there is apparent correlation between ibuprofen and reflux nephropathy. Keywords:Reflux Nephropathy, Ibuprofen, NSAID.
Authors and Affiliations
Parsa Yousefichaijan, MasoudRezagholi Zamenjany, Fatemeh Dorreh, Fakhreddin Shariatmadari, Yazdan Ghandi, Sara Khalighi
Keywords
Related Articles
- EP ID EP372433
- DOI -
- Views 73
- Downloads 0
Somatization in Mastalgia Patients: Is there a Relationship between Mastalgia and Somatization Symptoms?
Somatization can be defined as the physical complaints and symptoms that cannot be explained through physical findings and examinations. In the illnesses in which pain remains at the forefront, the manifestation of the e...
Coagulation Profiles an Indicator of Vascular Haemostatic Function in Chronic Renal Failure Patients Who Are on Renal Dialysis.
Renal disease is a common cause of death and disability in many countries throughout the world. Renal failure can be classified as acute and chronic depending upon the etiological factors. Chronic kidney disease (CKD) is...
Prevalence and Antibiogram of Gram Positive Organism Isolated from Patients of Urinary Tract Infection
Abstract: Urinary tract infection (UTI) is one of the most frequent types of nosocomial infections and probably affects about one-half of all people during their lifetimes. The predominant pathogen responsible for UTI is...
An Overview of Current Treatments of Migraine
Abstract: The name ‘migraine’ has its origin from the Greek word hemicrania, which means ‘half of the head’, indicating the main feature of migraine i.e it affects only half portion of the head. It is the most widespread...
Knowledge and awareness of the radiation safety among the medical students and resident doctors
Abstract: In day to day medical investigations radiations now become a must for the diagnosis. The radiations having most of the health risk for the doctors in constant contact with such procedures. During the learning p...