Regulation of Protein Degradation and Homeostasis by the Cytokine- Inducible Deubiquitinating Enzymes
Journal Title: International Journal of Immunotherapy and Cancer Research - Year 2018, Vol 4, Issue 1
Abstract
Ubiquitin-proteasome system (UPS) is the major signaling pathway responsible for regulating protein turnover in cells. Deubiquitinating enzymes (DUBs) have an important role in this signaling pathway by eliminating ubiquitins from substrates and inhibiting proteasomal degradation to maintain cellular homeostasis.
Authors and Affiliations
KH Baek
Keywords
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- DOI 10.17352/2455-8591.00001
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