Relapse of T-Cell Lymphoma as Isolated Brachial Plexus Neurolymphomatosis: A Case Report
Journal Title: Journal of Academic Research in Medicine - Year 2021, Vol 11, Issue 1
Abstract
Neurolymphomatosis (NL) is the neoplastic endoneurial invasion of the peripheral nervous system. It is a rare and challenging diagnosis, but it should be taken into account in the differential diagnosis of peripheral neuropathy, particularly in patients with a documented history of haematologic malignancy. Magnetic resonance (MR) neurography is very useful in diagnosis and especially when correlated with positron emission tomography/ computed tomography (PET/CT). In equivocal cases, nerve biopsy can be considered when the benefit outweighs the risk. We aimed to report a case of a 30-year-old male patient who was in complete remission from T-lymphoblastic lymphoma, presenting with clinical findings indicating initially ulnar entrapment. However, with the demonstration of brachial plexopathy with axonal loss in electrodiagnostic studies, MR imaging neurography dedicated to brachial plexus was carried out and revealed pathological enhancement associated with mild fluorodeoxyglucose (FDG) uptake on PET/ CT. Moreover, NL, due to the relapse of T-cell lymphoma, was diagnosed through incisional biopsy, showing diffuse infiltration of blast cells positive for terminal deoxynucleotidyl transferase, CD3 and CD10. Further, radiotherapy and systemic chemotherapy were initiated, and symptoms recovered with regression of pathological FDG uptake.
Authors and Affiliations
Kenan Kıbıcı, Berrin Erok, Ali Önder Atça , Gülçin Yeğen
Keywords
Related Articles
- EP ID EP694486
- DOI 10.4274/jarem.galenos.2020.3640
- Views 90
- Downloads 0
Do INI1 and E-cadherin Expression Loss Have Any Significance in Endometrial Carcinomas?
Objective: Endometrial carcinoma (EC) is a highly heterogeneous malignancy in terms of morphology, clinical course, response to treatment and prognosis. This study aimed to investigate the loss of INI1 (SWI/SNF family me...
Prevalence of Intra-spinal Pathologies in Adolescent Idiopathic Scoliosis Patients
Objective: To evaluate the prevalence of intra-spinal pathologies (ISP) in adolescent idiopathic scoliosis patients. Methods: We retrospectively reviewed all adolescent idiopathic scoliosis cases surgically treated in o...
A Rare Presentation of Retinoblastoma as a Fungating Orbital Mass: A Case Report
Retinoblastoma (RBL) arises from the precursor cells of the retinal neuroepithelium. It is the most common primary malignant intraocular tumor in children. Primary orbital RBL is an extraocular disease detected clinicall...
Is Vitamin D Important for Elderly Patients in Intensive Care?
Objective: According to the World Health Organization’s old age classification, 65-74 years is considered as young-old, 75-84 years as middle-old, and over 85 years as old-old. Effects of vitamin D on cardiac, renal, and...
The Effect of Video Information on Preoperative Anxiety Levels in Patients Undergoing Total Knee Replacement
Objective: The preoperative anxiety rate in patients waiting for elective surgery varies between 60% and 80%. We aimed to reduce preoperative anxiety in patients undergoing total knee replacement using a video demonstrat...