Relapsing Non Melanoma Skin Cancer in a Patient with Ulcerative Colitis Exposed to Long-Term Therapy with Thiopurines: Need for Regular Dermatological Screening
Journal Title: Journal of Dermatology Research and Therapy - Year 2016, Vol 2, Issue 3
Abstract
An increase of risk of malignancies such as lymphoma and non-melanoma skin cancer has been reported with the chronic use of immunomodulators in inflammatory bowel disease, particularly thiopurines. A case of a patient with ulcerative colitis after several years in immunosuppressive therapy developing multiple non-melanocytic skin neoplasms is described below.
Fluoroscopy-Induced Chronic Radiodermatitis
Fluoroscopy induced chronic radiation dermatitis (FICRD) is a rare complication which can be difficult to diagnose and treat. Recently fluoroscopy use has increased and the diagnostic and the theuropathic fluoroscopy pro...
Imatinib-Induced Erythema Nodosum : A Case Report and Literature Review
The list of drugs inducing an erythema nodosum is long and is extending. Their accountability is difficult to ascertain; rare observations relate positive drug provocation tests. Observation: We report a case of subintr...
Rapid Improvement of Hidradenitis Suppurativa Following Sleeve Gastrectomy
Severe obesity is commonly associated with dermatologic disorders such as intertrigo, psoriasis and hidradenitis suppurativa (HS). HS is a chronic inflammatory skin disease characterized by clusters of nodules, cysts, an...
Folliculotropic Mycosis Fungoides: A Clinicopathological Study of a Series of 10 Cases
Background: Folliculotropic mycosis fungoides (FMF) is a rare variant of cutaneous T-cell lymphoma, characterizedby the infiltration of atypical lymphocytes into hair follicles (folliculotropism). Design: A single centr...
Fluorescence in Situ Hybridization (FISH) Copy Number Abnormalities at 6p (RREB1), 6q (MYB), and 11q (CCND1) Reliably Distinguish Metastatic Versus Benign Melanocytic Lesions
Objectives: Malignant melanoma can be difficult to distinguish from a benign melanocytic lesion by histology. In this study, we investigated the sensitivity and specificity of FISH to distinguish between benign nevi and...