Relapsing Non Melanoma Skin Cancer in a Patient with Ulcerative Colitis Exposed to Long-Term Therapy with Thiopurines: Need for Regular Dermatological Screening
Journal Title: Journal of Dermatology Research and Therapy - Year 2016, Vol 2, Issue 3
Abstract
An increase of risk of malignancies such as lymphoma and non-melanoma skin cancer has been reported with the chronic use of immunomodulators in inflammatory bowel disease, particularly thiopurines. A case of a patient with ulcerative colitis after several years in immunosuppressive therapy developing multiple non-melanocytic skin neoplasms is described below.
New Insights and Therapeutic Implications in Cutaneous Melanoma
Melanoma is a highly aggressive tumour with poor prognosis in the metastatic stage that arises and evolves due to a myriad of genetic and epigenetic events. Among these, the interaction between epigenetic alterations (i....
Geometric Botulinum Toxin Injections: A Simplified Reproducible Approach for Symmetric Face Rejuvenation
Introduction: Different approaches have been described for botulinum toxin (BTX-A) injections for face rejuvenation. Most techniques are based on the experience of the injecting physician and his/her learning curve. We d...
Pyoderma Gangrenosum: A Review of Orthopedic Case Reports
Pyoderma gangrenosum (PG) is an uncommon disease characterized by necrotic ulcers that are often associated with underlying systemic disease. PG can occur at the surgical site following surgery, including orthopedic surg...
Relapsing Non Melanoma Skin Cancer in a Patient with Ulcerative Colitis Exposed to Long-Term Therapy with Thiopurines: Need for Regular Dermatological Screening
An increase of risk of malignancies such as lymphoma and non-melanoma skin cancer has been reported with the chronic use of immunomodulators in inflammatory bowel disease, particularly thiopurines. A case of a patient wi...
Folliculotropic Mycosis Fungoides: A Clinicopathological Study of a Series of 10 Cases
Background: Folliculotropic mycosis fungoides (FMF) is a rare variant of cutaneous T-cell lymphoma, characterizedby the infiltration of atypical lymphocytes into hair follicles (folliculotropism). Design: A single centr...