Relationship between Amiga Score and the Size of Esophageal Varycas Endoscopically On Patients of Cardiac Cirrhosis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Most patients with cardiac cirrhosis will have esophageal varices in the course of their illness. AIAG Score is a simple marker that can predict liver fibrosis with a good degree of accuracy and has been demonstrated in several studies. Based on the concept that liver fibrosis will ultimately lead to the occurrence of esophageal varices, non-invasive examination for liver fibrosis can be used as a predictor of esophageal varices. Research Method: cross-sectional study was conducted on 80 patients with cardiac cirrhosis at Adam Malik Hospital from June 2014 to June 2015. The diagnosis of cardiac cirrhosis was based on clinical, biochemical and ultrasound, and esophageal varices with endoscopy. The AIAG Score was calculated on all patients, with statistical analysis of Mann Whitney test and α = 5%. Results: Among 80 patients of cardiac cirrhosis with esophageal varices, 50% are caused by hepatitis B virus infection (HBV). Most research population has Child-Pugh C identification and F1 esophageal varices. AIAG Score on large varicose veins is significantly higher than on small varicose veins (0.99 ± 0.005 vs 0.9 ± 0.16; p <0.001). The value of cut-off AIAG Score > 0.994 in predicting the existence of large esophageal varices have a sensitivity of 82.5%, specificity of 72.5 %, positive predictive value of 75%, negative predictive value of 80.6 % Conclusion: AIAG Score is significantly associated with large esophageal varices. AIAG Score is a noninvasive marker, which is good for large esophageal varices in patients with cardiac cirrhosis.
Authors and Affiliations
Dedy M. Abu Bakar, Rustam Effendi-YS, Taufik Sungkar
Keywords
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