Relationship between Helicobacter Pylori, Chronic Idiopathic Urticaria and Atopic Dermatitis
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 70, Issue 11
Abstract
<em><strong>Background:</strong></em><em> Helicobacter pylori</em> (<em>H. pylori</em>) is the microorganism responsible for the most frequent and persistent bacterial infection worldwide. <em>H.pylori</em> infection affects nearly half of the world’s population. In the developing countries, the prevalence of infection is as high as 90%, whereas in the developed countries, excluding Japan, the prevalence is below 40% <strong><sup>(1)</sup></strong><strong><em>.</em></strong> An association between <em>H. pylori</em> infection and skin diseases such as chronic idiopathic urticaria and atopic dermatitis has been suggested <strong><sup>(</sup></strong><strong><sup>2</sup></strong><strong><sup>)</sup></strong><strong><em>.</em></strong> <strong>Aim of the work:</strong> this review aimed to focus on the relationship between <em>Helicobacter pylori</em>, chronic idiopathic urticaria and atopic dermatitis. This association was reviewed in the following lines. <strong>Methodology:</strong> we used scientific websites such as PubMed, Google Scholar and Research Gate to get related articles about this subject. <strong>Results: </strong>several studies have reported the presence of <em>H. pylori</em> DNA in environmental water sources. Diagnostic tests are usually divided into invasive (endoscopic-based) and noninvasive methods. Using proton-pump inhibitors (PPIs) in combination with several antibiotics such as amoxicillin plus clarithromycin or metronidazole have been considered as the first-line treatment. <strong>Conclusion: </strong><em>H. pylori</em> has a great prevalence among world’s population. <em>H. pylori</em> infection could play a role in the pathogenesis of a variety of skin diseases.
Authors and Affiliations
Eman Helal
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