Relationship Between Premature ventricular complexes and Neutrophil–Lymphocyte Ratio in asymptomatic healty young men
Journal Title: Medical Science and Discovery - Year 2015, Vol 2, Issue 4
Abstract
Background: Premature ventricular complexes (PVC) are a relatively common electrocardiographic abnormality presenting in individuals without overt cardiovascular disease. There is no clear mortality benefit from VPB suppression in asymptomatic patients. In addition, It has been showed that evidence for structural heart disease consistent with non-ischemic scarring possibly due to inflammation in patients with premature ventricular beats . This situation suggests that the mechanisms by which VPBs can be also generated with include clinical and subclinical inflammation. The neutrophil–lymphocyte ratio (NLR) is an easy, cheap, noninvasive, and universally available laboratory marker used to evaluate clinical and subclinical systemic inflammation.We investigated the NLR in asymptomatic healty young men with PVC(structural heart disease excluded with cardiac magnetic resonance imaging) compared with controls.Methods: The study group consisted of 21 asymptomatic(or atypical complaint) healty young men with PVC ( mean age 22.7 ± 2.0 years.Results:There were no significant differences between the 2 groups with respect to age, gender, body mass index, smoking, as well as glucose, creatinine, total cholesterol, triglyceride, LDL-C, HDL-C, hemoglobin levels, white blood cell count, and red cell distribution width. The NLR was significantly higher among the men with PVC than that of the control group (2.7 ±0.7 vs 1.5 ± 0.4, respectively; P < .001).Conclusions: We found that the NLR is significantly elevated in asymptomatic healty young men with PVC compared with control participants. The increased NLR values might indicate subclinical and clinical inflammation in asymptomatic healty young men with PVC ,and we must consider that there
Authors and Affiliations
Erkan Kibrisli, Ahmet Yilmaz, Sinan Iscen, Salim Ozenc, Duran Tok, Adem Parlak
Keywords
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