Relationship Between Tri-Iodothyronine (T3) And Body Mass Index In Healthy Euthyroid Subject In Khartoum State
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Body weight and overt thyroid dysfunction are associated ,although the effect of hypothyroidism and hyperthyroidism on body weight have been clearly demonstrated there is no Sufficient data on the relationship between body mass index and minor differences within the normal range of thyroid hormones .This study was carried out to investigate the relationship of fluctuations of triiodothyronine (t3) with body mass index in euthyroid subject. 90 blood samples were collected from euthyroid healthy individual of known age , gender , weight , height and biochemical picture of triiodothyronine(t3) in period between June to October 2016, chosen from general population in Khartoum state. The individual are classified into three groups according to body mass index underweight group with BMI less than 18.9, overweight group with BMI more than 24.9 as case groups and 30 apparently healthy individual with normal weight , BMI ( 18.9 – 24.9 ) serve as control group . T3 was measured by enzyme immunoassay test kit. Data was analyzed using SPSS computer program. The study showed that, there was significant increase in the mean of serum t3 level between three groups ( underweight group , normal weight group and overweight group) (1.73±0.34ng/ml , 1.46±0.51ng/ml , 0.94±0.47ng/ml ) respectively. ( p.value .000). There was a significant increase in mean when compared underweight group with normal weight group (1.73±0.34 versus 1.46±0.51, p. value .024) .also mean was significantly increase when compared normal weight with overweight.( 1.46±0.51 versus 0.94±0.47, p- value =0.000 ), there was significant increase in mean when compared underweight group vs overweight group(1.73±0.34 versus 0.94±0.47 ,p.value .00) . There was significantly weak negative correlation between serum t3 and body mass index in three groups ( r= - 0.500 / p= 0.00), also there was insignificant weak negative correlations between serum t3 and age of study groups(r= -0.169/p= .111 ). In conclusion, there was significant increase in t3 level in study groups and there was negative correlation between BMI,t3 and age.
Authors and Affiliations
Asmaa Basheer Ahmed, Nuha Eljaili Abubaker
Keywords
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- EP ID EP255724
- DOI 10.9790/0853-1609021822
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