RELATIONSHIP OF THE CONDITION OF THE MYOCARDIUM WITH INFRINGEMENTS THE CALCIUM AND PHOSPHORUS METABOLISM INPATIENTS WITH DIABETIC NEPHROPATHY
Journal Title: УКРАЇНСЬКИЙ ЖУРНАЛ НЕФРОЛОГІЇ ТА ДІАЛІЗУ - Year 2017, Vol 2, Issue 54
Abstract
Objective: To establish the possible relationship between changes in cardiac hemodynamics and im-paired phosphate-calcium metabolism and content FGF 23.Patients and Methods: 260 people with diabetic nephropathy , 64 people with hypertension and 20 healthy individu-als were surveyed . Studied the state of the myocardium and cardiac hemodynamics, blood levels of calcium, phosphorus and FGF 23.Results and conclusions: between the state of myocardium , cardiac hemodynamics and content FGF23, phos-phorus and calcium are closely interrelated, which is likely mediated through specific receptor apparatus of myocardium and through immunoinflammatory mechanisms. However, the specific mechanisms of action system FGF23 / phosphorus-calcium exchange for anatomical and functional myocardial changes require further investigation.Топчій Іван Івановичitopchiy@yandex.ua
Authors and Affiliations
I. I. Topchii, V. P. Denisenko, O. M. Kirienko, P. S. Semenovykh, Yu. S. Yakimenko, V. V. Mazii
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