RELATIVE GENE EXPRESSION ANALYSIS FROM URINE SAMPLES OF PATIENTS WITH PROSTATE DISEASE
Journal Title: Genetics & Applications - Year 2018, Vol 2, Issue 1
Abstract
Conventional screening and diagnostic procedures are leaned on PSA (Prostate specific antigene) which is not specific for prostate cancer and frequently leads to unnecessary invasive procedures for the exclusion of malignant disease. It is estimated that approximately 50% of persons underwent tissue biopsy is done upon false positive PSA value. Therefore a proper and timely differential diagnosis of malignant disease using non-invasive techniques remains one of the biggest challenges in medicine. Urine is the invaluable source of biological information contained in small molecules i.e. RNA that is easily reachable and detectable using molecular genetics techniques. We describe economical and fast method for relative expression analysis applicable to any target gene from urine samples and associated risk factors. Efficient non-invasive method for identification of malignant or high risk cases prove useful in reduction of patient distress during the diagnostic procedure and healthcare costs
Authors and Affiliations
Jasmin Ramić, Benjamin Kulovac, Naida Lojo-Kadrić, Maida Hadžić, Naris Pojskić, Đenana Eminagić, Lejla Pojskić
Keywords
Related Articles
- EP ID EP349550
- DOI 10.31383/ga.vol2iss1pp19-24
- Views 120
- Downloads 0
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