Release of muscle α-actin into serum after intensive exercise
Journal Title: Biology of Sport - Year 2010, Vol 27, Issue 4
Abstract
Purpose: To study the effects of high-level matches on serum alpha actin and other muscle damage markers in teams of rugby and handball players. Methods: Blood samples were drawn from 23 sportsmen: 13 rugby players and 10 handball players. One sample was drawn with the player at rest before the match and one immediately after the match. Immunoassays were used to determine troponin I, troponin T, LDH, and myoglobin concentrations. Western blot and densitometry were used to measure α-actin concentrations. Muscle injury was defined by a total CK value of > 500 IU/L (Rosalki method). Results: Mean pre- and post-match serum alpha-actin values were, respectively, 7.16 and 26.47 μg/ml in the handball group and 1.24 and 20.04 μg/ml in the rugby team. CPK, LDH and myoglobin but not troponin 1 levels also significantly differed between these time points. According to these results, large amounts of α-actin are released into peripheral blood immediately after intense physical effort. Possible cross-interference between skeletal and cardiac muscle damage can be discriminated by the combined use of α-actin and troponin I. Conclusion: The significant increase in alpha-actin after a high-level match may be a reliable marker for the early diagnosis and hence more effective treatment of muscle injury.
Authors and Affiliations
A Martínez-Amat, J. A. Marchal, J Prados, F Hita, H Boulaiz, I Martín, C Melguizo, O Caba, R Ortiz, A. R Rama
Keywords
Related Articles
- EP ID EP59026
- DOI -
- Views 78
- Downloads 0
THEORETICAL AND EXPERIMENTAL STUDY ON DURABILITY OF THE CALCANEAL TENDON AND THE PATHOMECHANISM OF ITS ATRAUMATIC, SUBCUTANEOUS BREAK
The pathology of the calcaneal tendon (Achilles) presents a serious medical and social problem. This tendon is the strongest plantar flexor of the foot that plays a fundamental role in the accomplishment of human gait. A...
CHANGES IN MAXIMAL STRENGTH AND BODY COMPOSITION AFTER DIFFERENT METHODS OF DEVELOPING MUSCLE STRENGTH AND SUPPLEMENTATION WITH CREATINE, L-CARNITINE AND HMB
The aim of the present study was to assess the effects of bodybuilding training combined with administration of L-carnitine, weightlifting training combined with administration of creatine, and isometric training combine...
AUTONOMIC CONTROL OF HEART RATE AFTER EXERCISE IN TRAINED WRESTLERS
The objective of this study was to establish differences in vagal reactivation, through heart rate recovery and heart rate variability post exercise, in Brazilian jiu-jitsu wrestlers (BJJW). A total of 18 male athletes w...
MUSCLE DAMAGE AFTER A TENNIS MATCH IN YOUNG PLAYERS
The present study investigated changes in indirect markers of muscle damage following a simulated tennis match play using nationally ranked young (17.6 ± 1.4 years) male tennis players. Ten young athletes played a 3-hour...
THE EFFECTS OF BACK EXTENSION TRAINING ON BACK MUSCLE STRENGTH AND SPINAL RANGE OF MOTION IN YOUNG FEMALES
The objective of this study was to determine the effects of a 10-week dynamic back extension training programme and its effects on back muscle strength, back muscle endurance and spinal range of motion (ROM) for healthy...