Renal Function Impairment In Hypothyroid Patient: A Study From Eastern India
Journal Title: International Journal of Medical Science And Advanced Clinical Research (IJMACR) - Year 2019, Vol 2, Issue 3
Abstract
Objectives: Thyroid hormones are essential for adequate development and maintenance of renal function. Hypothyroidism is associated with decreased glomerular filtration. Present study has been intended to determine the degree of renal impairment in hypothyroid status and its relation with treatment. Methods: This was a longitudinal & prospective study, involving clinical & diagnostic evaluation and follow up and was conducted on 100 newly diagnosed patient of primary hypothyroidism (TSH value ≥ 6 mIU/ml). Thyroid hormone parameters and renal parameters were analyzed before and 3 months after initiation of supplementation. Results: The study showed mean serum TSH value before treatment was 44.70±31.59 and after treatment was 2.69±1.06. The difference of TSH level before and after treatment was significant (p=0.000). Mean serum creatinine value before and after treatment were 0.95±0.24 and 0.83±0.18 respectively, which was significant (p=0.000). Mean creatinine clearance level before and after therapy were 77.62±7.01 and 87.45±6.61. The difference between creatinine clearance before and after therapy was significant (p=0.000). Conclusions: The assessment of thyroid function should be routinely carried out for evaluation of patients presenting with deranged renal function.
Authors and Affiliations
Dr. Manoj Kr. Mahata
Keywords
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