RENAL FUNCTION IN SUDANESE PATIENTS WITH ESSENTIAL HYPERTENSION
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2017, Vol 4, Issue 10
Abstract
Background: The kidney is an important target of hypertension. Understanding of renal function is critical for prevention of hypertension and renal disease. Objectives: The main objective of this study was to detect the effect of primary hypertension on renal function in Sudanese male patients. Material and Method: This case-control and cross-sectional study assessed renal function in Sudanese male patients with essential hypertension. Hypertensive and normotensive subjects were randomly selected. Result: Mean creatinine clearance was 57.8±33.9ml/min in hypertensive cases. Thirty five percent of hypertensive group had >1.5 mg/dl serum creatinine. Urea was found significantly high in 25.8% of hypertensive cases and coincided with those having serum creatinine> 1.7 mg/dl. Mean uric acid was 7.71 mg/dl and 6.03 mg/dl in hypertensive and normotensive subjects respectively. Serum sodium increased in hypertensive cases insignificantly; potassium elevated in 21.2% and 4.2% in hypertensive and normotensive subjects respectively. Albuminuria, casts and RBCs were present in urine of hypertensive patients. Conclusion: Serum uric acid may be a more sensitive test for renal function. Strong association was found between essential hypertension and renal biomarkers.
Authors and Affiliations
Hind M. Beheiry
Keywords
Related Articles
- EP ID EP630973
- DOI -
- Views 145
- Downloads 0
LYCOPENE AND ATHEROGENIC RISK FACTORS: A REVIEW
Coronary heart disease is marked as the third–fourth largest global deaths worldwide by addressing the attributes of high increase hazard ratios across multiple variables: Hypertension, Dyslipidemia, Elevated cholesterol...
EARLY INFANT DETECTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION USING DRIED BLOOD SPOTS AT A TERTIARY CARE HOSPITAL IN RIVERS STATE, NIGERIA
Children born to HIV-positive mothers are likely to acquire maternal antibody which has made early infant detection of HIV challenging, using conventional screening methods. This study was aimed to provide early diagnosi...
THIOBENCARB DECREASES TESTICULAR GERM CELL PROLIFERATION, INHIBITS SPERMATOGENESIS AND INCREASES APOPTOSIS: HISTOLOGICAL AND IMMUNOHISTOCHEMICAL ASSESSMENTS
Background: Herbicides were found to induce harmful health effects as oxidative stress, reproductive disorders and histopathological alterations in vital organs. Thiobencarb is heavily used in rice cultivation in Egypt....
GARLIC AS ALTERNATIVE THERAPY TO TREAT UROPATHOGENE BACTERIA IN WOMEN WITH URINARY TRACT INFECTION IN LOMÉ, TOGO
The urinary tract infection (UTI) is the most common bacterial infection, especially in women. The increased incidence of UTIs, at the last decades have paralleled with the growing emergence of antibiotic resistance. The...
THE BODY MASS INDEX OF SELECTED MALE AND FEMALE ADULTS SUBJECTS IN YENAGOA, AND SOME RURAL AREAS OF BAYELSA STATE NIGERIA.
The body mass index of some adult subjects between the ages of twenty to sixty five (20-65) years were studied in Bayelsa State. The number of subjects studied were two hundred, comprising one hundred and four males and...