Renal pathology in maternal deaths: An autopsy study
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 3
Abstract
A spectrum of renal pathology is observed during pregnancy so our main objective was to study the gross pathology and microscopy of the kidney in cases of maternal death and to establish a clinicopathological correlation This was a crosssectional study of all medical autopsies performed on deaths related to pregnancy at our tertiary care hospital over a period of 7 years In 166 autopsies pathology was observed in 42 cases and the kidneys were unremarkable in 124 cases The most common renal pathology observed was acute tubular necrosis 22 cases followed by acute pyelonephritis 7 cases disseminated intravascular coagulation with fibrin thrombi 7 cases diabetic nephropathy 3 cases sickle cell anemia 1 case tuberculosis kidney 1 case and thrombotic microangiopathy 1 case Renal pathology was observed in 253 of autopsies performed on maternal death which contributed to a significant number of maternal mortalities and morbidities The incidence of acute renal failure was 1428 in our study Apart from obstetric complications eg antepartum hemorrhage postpartum hemorrhage pregnancyinduced hypertension infections eg pyelonephritis were associated with septicemia deranged renal function tests and acute renal failure KeywordsAutopsy Maternal Death Renal Pathology
Authors and Affiliations
Shruti Chandrakar, Anitha Padmanabhan
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