Renal Protective effects of Melatonin in rat treat by Gemcitabine
Journal Title: International Journal of Veterinary Science and Research - Year 2017, Vol 3, Issue 2
Abstract
Nephrotoxic side effects of gemcitabine have been reported in patients receiving this drug medication. Melatonin is a potent free radical scavenger and antioxidant and has protective effects against ischemic damage. In the present study, we examined the relationship between the renal protective effects of melatonin in tubular damage induced by gemcitabine. This study was conducted simultaneously as a case of 48 male wistar rat, weighing approximately 20 ± 250 g and aged 8 weeks were used. The rats were randomly divided into 3 groups.
Authors and Affiliations
Mortazavi Pejman, Ahmadnezhad Behnam, Pousty Iraj, Panahi Negar, Aghazadeh Mitra, Shalikar Mostafa, Ramezani Vahid, Meybodi Maryam Aghaie
Keywords
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- EP ID EP554168
- DOI 10.17352/ijvsr.000025
- Views 33
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