Renin angiotensin-aldosterone system blockers: chronic kidney disease and cardiovascular risk
Journal Title: Нирки - Year 2018, Vol 7, Issue 2
Abstract
Reducing the risk of cardiovascular events is one of the most topical issues of modern medicine. Patients with chronic kidney disease stage 3 or lower, according to international guidelines, refer to the group with high and very high cardiovascular risk. At the moment, all the existing recommendations share the view that the first-line drugs for lowering blood pressure among this group of patients are renin-angiotensin-aldosterone system blockers. When renal and cardiovascular pathologies are combined, in addition to traditional risk factors, there are non-traditional kidney risk factors too (anaemia, hyperhydration, hypercoagulation, etc.). Combined antihypertensive therapy is preferable in order to achieve more significant reduction in global cardiovascular risk and closer control of blood pressure.
Authors and Affiliations
D. D. Ivanov, O. V. Kuryata, I. P. Garmysh
Keywords
Related Articles
- EP ID EP280815
- DOI 10.22141/2307-1257.7.2.2018.127393
- Views 65
- Downloads 0
Antibiotic Resistance in Nephrological Practice
The problem of antibiotic resistance is a serious threat to the global public health and requires action by both the state and the public. The World Health Organization identified 15 most dangerous and prevalent superbug...
Antibiotic therapy of uncomplicated pyelonephritis
The article reviews modern European guidelines on antibacterial treatment of uncomplicated pyelonephritis. Three main components of successful treatment are described: evidence-based antibiotic therapy, individual doctor...
Cardiorenal Syndrome: Diagnosis and Treatment
In the diagnosis of cardiorenal syndrome (CRS), the biological markers are widely used, they can be applied to identify the pathophysiological stages of CRS, to assess the amount of risk, prognosis and outcome, as well a...
Hypomagnesemia in Chronic Kidney Disease: Problem or Individual Characteristics of Certain Patients?
The article considers the problem of magnesium deficiency in patients with chronic kidney disease. It requires special attention from clinicians due to the increased risk of cardiovascular complications. The study reveal...
Acute Interstitial Nephritis: the Value of Morphological Diagnosis
The clinical case demonstrates the importance of and the need for kidney biopsy for morphological verification of the diagnosis to determine the therapeutic approach and management of patients with kidney disease.