REPARATIVE OSTEOGENESIS DURING TREATMENT OF FRACTURE UNDER TRANSOSSEOUS OSTEOSYNTHESIS AND INTRAMEDULLARY INSERTION OF WIRES WITH HYDROXYAPATITE COATING

Abstract

Background: The problem of improving medical care for patients with the locomotor system injuries is very important especially last time. Material and Methods: Canine open comminuted tibial fractures modelled experimentally, wires with hydroxyapatite coating inserted intramedullary, osteosynthesis performed with the Ilizarov fixator. Regenerated bones investigated 14-360 days after surgery using the techniques of light microscopy, scanning and transmission electron microscopy, and X-ray electron probe microanalysis for histologic sections . Results: It has been found that a zone of active reparative osteo- and angiogenesis forms around the wires, as well as a bone sheath with the properties of osteogenesis conductor and inductor. Fracture consolidation occurs early according to the primary type without cartilaginous and connective tissue formation in bone adhesion. Presented morphological characteristics endovasal angiogenesis. Conclusion: The results of the study evidence of the positive effect of intramedullary wires with hydroxyapatite coating on the course and intensity of reparative osteogenesis during fracture healing.

Authors and Affiliations

Iurii M. Irianov| Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), Ul'ianova Street, 6. Kurgan, 640014. Russia, Arnold V. Popkov| Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), Ul'ianova Street, 6. Kurgan, 640014. Russia, Nikolay A. Kiryanov| Izhevsk state medical academy, Kommunarov str., 281, Izhevsk, Russia, Corresponding author email: kirnik@list.ru, Tatiana Iu. Karaseva| Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), Ul'ianova Street, 6. Kurgan, 640014. Russia, Evgenii A. Karasev| Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), Ul'ianova Street, 6. Kurgan, 640014. Russia

Keywords

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  • EP ID EP11388
  • DOI 10.5958/2319-5886.2015.00054.5
  • Views 229
  • Downloads 12

How To Cite

Iurii M. Irianov, Arnold V. Popkov, Nikolay A. Kiryanov, Tatiana Iu. Karaseva, Evgenii A. Karasev (2015). REPARATIVE OSTEOGENESIS DURING TREATMENT OF FRACTURE UNDER TRANSOSSEOUS OSTEOSYNTHESIS AND INTRAMEDULLARY INSERTION OF WIRES WITH HYDROXYAPATITE COATING. International Journal of Medical Research & Health Sciences (IJMRHS), 4(2), 294-298. https://europub.co.uk/articles/-A-11388