REPARATIVE OSTEOGENESIS DURING TREATMENT OF FRACTURE UNDER TRANSOSSEOUS OSTEOSYNTHESIS AND INTRAMEDULLARY INSERTION OF WIRES WITH HYDROXYAPATITE COATING
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2015, Vol 4, Issue 2
Abstract
Background: The problem of improving medical care for patients with the locomotor system injuries is very important especially last time. Material and Methods: Canine open comminuted tibial fractures modelled experimentally, wires with hydroxyapatite coating inserted intramedullary, osteosynthesis performed with the Ilizarov fixator. Regenerated bones investigated 14-360 days after surgery using the techniques of light microscopy, scanning and transmission electron microscopy, and X-ray electron probe microanalysis for histologic sections . Results: It has been found that a zone of active reparative osteo- and angiogenesis forms around the wires, as well as a bone sheath with the properties of osteogenesis conductor and inductor. Fracture consolidation occurs early according to the primary type without cartilaginous and connective tissue formation in bone adhesion. Presented morphological characteristics endovasal angiogenesis. Conclusion: The results of the study evidence of the positive effect of intramedullary wires with hydroxyapatite coating on the course and intensity of reparative osteogenesis during fracture healing.
Authors and Affiliations
Iurii M. Irianov| Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), Ul'ianova Street, 6. Kurgan, 640014. Russia, Arnold V. Popkov| Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), Ul'ianova Street, 6. Kurgan, 640014. Russia, Nikolay A. Kiryanov| Izhevsk state medical academy, Kommunarov str., 281, Izhevsk, Russia, Corresponding author email: kirnik@list.ru, Tatiana Iu. Karaseva| Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), Ul'ianova Street, 6. Kurgan, 640014. Russia, Evgenii A. Karasev| Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), Ul'ianova Street, 6. Kurgan, 640014. Russia
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- EP ID EP11388
- DOI 10.5958/2319-5886.2015.00054.5
- Views 262
- Downloads 12
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