Research progress in gonioscopy-assisted transluminal trabeculotomy in the treatment of glaucoma
Journal Title: Eye Science (Yanke Xuebao) - Year 2023, Vol 38, Issue 6
Abstract
As a modified trabeculotomy, Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) is a new type of minimally invasive glaucoma surgery developed at home and abroad in recent years. GATT inserts a microcatheter (iTrack) into the Schlemm's canal and advance the catheter through the canal circumferentially 360°, then circumferentially fracture the trabecular meshwork and inner wall of Schlemm's canal. This method can reduce intraocular pressure by increasing the outflow of aqueous humor. The physiological outflow pathway of aqueous humor is reconstructed, which can avoid the resistance of trabecular meshwork and realizing the direct entry of the aqueous humor directly into the collector channel from the anterior chamber. With a wide range of indications, GATT is mainly used in open-angle glaucoma, including primary open-angle glaucoma and secondary open-angle glaucoma, and is also used in primary closed-angle glaucoma. Additionally, GATT can be the preferred surgical modality for open-angle glaucoma, as it has the following advantages: minimally invasive, independent of filtration bleb, can significantly reduce the use of medications, stable medium- and long-term efficacy, high safety, and has fewer sight-threatening complications. In order to provide a reference for clinical application, this article reviews the indications, mechanism of action, surgical procedures, effectiveness, complication and factors affecting therapeutic effect.
Authors and Affiliations
Caixia WANG, Yu HE
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