Research progress in promotion of bone regeneration and repair with exosomes derived from mesenchymal stem cell
Journal Title: Biomedical Transformation - Year 2023, Vol 4, Issue 2
Abstract
Mesenchymal stem cell exosomes (MSC-Exos) play an important role in mediating bone tissue regeneration and repair. In addition to participating in bone regeneration and repair by activating Wnt/β-catenin signaling pathway, MSC-Exos also actively promote the establishment of bone tissue regeneration microenvironment by participating in immune regulation. This review aims to summarize the regulatory effects and possible mechanisms of MSC-Exos on bone regeneration and repair, in order to provide a new research way for the treatment of bone metabolism-related diseases.
Authors and Affiliations
Da Lijun, Song Feixue, Teng Yuanjun, Wang Zunlin, Li Enxi, Liu Jinjin
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