Research progress of esketamine and postoperative delirium
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 8
Abstract
Postoperative delirium (POD) is a common complication in elderly patients after surgery, significantly affecting prognosis and increasing mortality rates. The underlying mechanisms of POD remain unclear, with diverse risk factors making prevention difficult and treatment outcomes unsatisfactory. Esketamine is a high-affinity N-methyl-D-aspartate (NMDA) receptor antagonist known for its anesthetic and analgesic properties. Besides its widespread use in perioperative anesthesia and pain management, esketamine has shown promising clinical applications across various disciplines including psychiatry and critical care. This review summarizes recent advances and mechanisms of esketamine in preventing and treating POD, offering new insights for clinical practice.
Authors and Affiliations
GAO Shilong, ZHANG Peifu, WANG Enqiang, WANG Qifang, YAO Zeyu
Keywords
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- EP ID EP743087
- DOI 10.13429/j.cnki.cjcr.2024.08.004
- Views 20
- Downloads 0
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