Research progress of the bone marrow mesenchymal stem cells to treat retinal neovascular disease
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 4
Abstract
Retinal neovascular disease is not an independent eye disease, which is more common seen in many other eye diseases spontaneously and cause serious damage to vision, such as retinopathy of prematurity, diabetic retinopathy, age-related macular degeneration, retinal central venous obstruction and retina venous inflammation, which present retinal neovascularization. The loss of normal blood vessels structure and function, causing pathological bleeding, oozing, edema and retinal detachment and other pathological changes, they are the main reason for loss of vision, which has become a worldwide blindness disease. At present, the main treatment for the disease include of laser occlusion, vitrectomy, repeated vitreous cavity injection of anti-vascular endothelial growth factor, those treatment has significant curative effect, but cannot prevent relapse of the disease. There is still no long-term effective treatment method nowadays. The emergence of stem cell therapy has provided potential alternative therapies. In this review, the latest application of bone marrow mesenchymal stem cells(BMSCs)in retinal neovascular disease will be discussed and present its migration advantages and promising clinical application prospects.
Authors and Affiliations
Guo-Xing Xu
Keywords
Related Articles
- EP ID EP656097
- DOI 10.3980/j.issn.1672-5123.2018.4.11
- Views 133
- Downloads 0
Multivariate analysis of corneal endothelial cell count reduction after cataract surgery
AIM:To investigate the factors related to the decrease of corneal endothelial cell number after phacoemulsification in cataract patients. <p>METHODS: We selected 98 patients(120 eyes)in Ophthalmic Center from July 2014 t...
Curative effect of extra-panretinal photocoagulation on proliferative diabetic retinopathy during vitreous operation
AIM: To discuss the curative effect of extra-panretinal photocoagulation on proliferative diabetic retinopathy(PDR)during vitreous operation. <p>METHODS: We conducted a retrospective analysis of 70 diabetic retinopathy p...
Comparison of polymethylmethacrylate versus hydrophobic acrylic lenses for primary intraocular lens implantation in pediatric cataract surgery
AIM: To compare the visual results and postoperative complications of polymethylmethacrylate(PMMA)and hydrophobic acrylic intraocular lenses(IOLs)in children who underwent cataract extraction with primary IOL implantatio...
Advances on biological indicators of diabetic retinopathy and characteristic peculiarities
Diabetic Retinopathy(DR)has gradually worsening and lingering, which is the leading cause of global young people blindness. With the progression of the disease, patients with diabetes mellitus(DM)will have different degr...
Evaluation of visual function and quality of life in patients with age-related macular degeneration after treatment
AIM: To evaluate the anatomic parameters, visual function and quality of life(QOL)in patients with age-related macular degeneration(ARMD)who were transferred from Ranibizumab to Conbercept. <p>METHODS: Twenty patients(29...