Research progress of transcranial alternating current stimulation in the treatment of cognitive impairment in neuropsychiatric diseases
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 1
Abstract
Cognitive dysfunction is the impairment of higher brain functions. Cognitive impairment caused by neuropsychiatric diseases has caused serious impact on patients' quality of life and the outcome of the disease. The transcranial alternating current stimulation (tACS) improves cognitive function by modulating neural oscillations of specific frequencies, affecting the release of neurotransmitters such as serotonin and dopamine, and enhancing local and distal synchronization of brain networks. Specific frequencies of tACS can improve the cognitive impairment caused by Alzheimer disease (AD), schizophrenia, and depression, among which the gamma and theta frequencies of tACS have the most significant effects on cognitive function. tACS has high safety and low operational difficulty, and has great potential to improve cognitive function.
Authors and Affiliations
Xuelin ZHANG, Qiuli YANG, Xiaying SI, Peishan HUANG, Ke WANG, Yi MIAO, Qiangli DONG
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