Research Progress of Yihuang Decoction and Prediction Analysis on Quality Markers
Journal Title: Journal of Experimental and Clinical Application of Chinese Medicine - Year 2024, Vol 5, Issue 1
Abstract
Background: Yihuang Decoction, a classical prescription found in Fu Qingzhu's Obstetrics and Gynecology, is formulated with fried Dioscoreae Rhizoma, fried Euryales Semen, wine-fried Plantaginis Semen, salt-fried Phellodendri Chinensis Cortex and Ginkgo Semen. Quality marker (Q-marker) plays a crucial role in promoting the standardization of the quality of traditional Chinese medicine (TCM). Hence, this study aimed to predict and analyze the Q-marker of Yihuang Decoction based on TCM Q-marker theory. Methods: A comprehensive review of relevant literature and the TCMSP database was conducted to investigate the chemical constituents, pharmacological effects, and clinical applications of Yihuang Decoction. Furthermore, the study predicted the Q-marker of Yihuang Decoction by considering its effectiveness, specificity, measurability, transmissibility and traceability, and compatibility, as per the concept of Chinese medicine Q-marker. Results: Yihuang Decoction exhibits pharmacological effects such as anti-inflammation and immune modulation, anti-bacteria and anti-virus properties. Clinically, it is mostly used to treat inflammation of the female reproductive system, including vaginitis, cervicitis and pelvic inflammation. According to analysis and prediction, it was suggested that allantoin, diosgenin, gallic acid, α-tocopherol, bilobalide, ginkgolide A, ginkgolide B, berberine, phellodendrine, magnoflorine, geniposidic acid and verbascoside could serve as Q-markers of Yihuang Decoction. Conclusion: This review establishes a foundation for the research and development of Yihuang Decoction, and providing a crucial scientific reference for ensuring its comprehensive quality control and enhancing evaluation standards.
Authors and Affiliations
Menggai Zhang, Xue Liu, Hehe Shi, Yinyue Xu, Longbiao Luo, Lijin Yu, Yitao Wang, Sicen Wang, Wanghui Jing
Keywords
Related Articles
- EP ID EP746599
- DOI https://doi.org/10.62767/jecacm501.7012
- Views 63
- Downloads 1
Research Progress of Yihuang Decoction and Prediction Analysis on Quality Markers
Background: Yihuang Decoction, a classical prescription found in Fu Qingzhu's Obstetrics and Gynecology, is formulated with fried Dioscoreae Rhizoma, fried Euryales Semen, wine-fried Plantaginis Semen, salt-fried Phellod...
Exploring the Potential of Lotus Leaf and Its Bioactive Compounds for Anti-obesity Interventions
The complex syndrome of obesity is a complex syndrome associated with various metabolic disorders, poses significant threats to human health. Many weight loss medications have the potential to rapidly treat obesity, howe...
Research Progress on the Basic Pharmacodynamic Substance and Mechanism of Citri Sarcodactylis Fructus in Relieving Anxiety
Anxiety disorder resulting from the interaction of psychological factors-caused anxiety and mood disorder symptoms is one of the clinical mental diseases. Excessive worry, nervousness and fear often bring about several n...
Effect of Jinhuahecha—A Fermented Green Tea on DSS-Induced Ulcerative Colitis in Mice and Its Preliminary Pharmacological Mechanism
Background: Ulcerative colitis (UC) is an inflammatory bowel disease. Jinhuahecha (JHHC)-a fermented green tea is obtained by micro-fermentation of Anji white tea (AJWT) inoculated with high-purity "E. cristatum". Purpos...
Rhizoma Zedoariae Inhibits G-CSF-Induced MDSCs-like Differentiation of THP-1 Cells
Objective: Rhizoma Zedoariae is widely used in the treatment of solid tumors in China, but there has been no deep research on its role in the formation of timmunosuppressive environments mediated by myeloid-derived suppr...