Research progress on hepatitis E virus and blood safety
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 4
Abstract
Hepatitis E virus (HEV) is one of the main reasons of acute viral hepatitis. Although the majority of hepatitis E virus infection in humans is transmitted by fecal-oral route around the world, transfusion-transmitted HEV (TT-HEV) has attracted more and more attention as an emerging global health problem. Worldwide, 0.001 3%-0.281 0% of blood donors are HEV virus asymptomatic infection, and 0.27%-60.50% of blood donors have anti-HEV immunoglobulin antibody IgG. Blood recipient could get infected with HEV even if viral load in the blood is extremely low, which poses a great threat to blood safety. Therefore, HEV screening in blood donors has become an important concern in many countries. This article reviews the evidence and typical cases of TT-HEV, as well as the detection protocols and results of HEV screening in different countries, in order to provide evidence for whether HEV screening should be included in routine screening items for voluntary blood donors in China.
Authors and Affiliations
Miao LIU
Keywords
Related Articles
- EP ID EP738536
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.04.017
- Views 35
- Downloads 0
Research progress of platelets and their derivatives based drug delivery systems
Platelets play an important role in physiological and pathological activities such as thrombosis, inflammation and tumorigenesis. At present, the application of platelets in drug delivery systems is increasingly studied....
Serological and molecular biological characteristics of hepatitis B vaccinated donors with asymptomatic chronical infection in Shenzhen
Objective To investigate asymptomatic infection of hepatitis B virus(HBV) among hepatitis B vaccinated donors in Shenzhen, and analyze its serological and molecular characteristics. Methods The HBsAg ELISA positive blood...
Effect of IgG dimer concentration on the binding ability of IgG Fc fragment in IVIG to THP-1 cell surface receptors
Objective To investigate the effect of immunoglobulin G (IgG) dimer concentration of intravenous immunoglobulin (IVIG) on the binding ability of IgG Fc fragment to THP-1 cell surface receptors. Methods Firstly, protein p...
Research progress on the role of red blood cells in infectious diseases
As the most abundant cells in blood, red blood cells have been gradually found to not only transport oxygen and carbon dioxide, but also participate in immune regulation in many ways. Recently, many studies have found th...
Research status of additives related to platelet preservation
Platelets play an important role in hemostasis, inflammation, tumor metastasis, wound healing and defense response, but its routine storage requires a specific temperature and the storage time is generally limited to 5 ~...