Research progress on severe pertussis in infants and young children
Journal Title: Journal of Clinical Pediatrics - Year 2025, Vol 43, Issue 5
Abstract
Pertussis is highly contagious. With the increase in the incidence rate of pertussis in recent years, pertussis outbreaks have even occurred in some areas. The recurrence of pertussis has attracted widespread attention, among which severe pertussis poses a great threat to the life and health of infants and young children. Elevated white blood cell count, pulmonary hypertension, non-vaccination and mixed infection are all associated with severe pertussis. Due to the lack of typical clinical symptoms and signs in infants and young children in the early stage, they often fail to receive timely diagnosis and treatment, which can easily lead to severe pertussis. Therefore, it is crucial to make an accurate diagnosis and provide timely treatment for pertussis. This article reviews the pathogenesis, treatment and prevention of severe pertussis in infants and young children, in order to deepen the clinician's understanding of severe pertussis and provide reference for the prevention and treatment of severe pertussis.
Authors and Affiliations
Shiyi XU, Min DU, Lixia BAI, Aihong LIU
Keywords
Related Articles
- EP ID EP766819
- DOI 10.12372/jcp.2025.24e0793
- Views 10
- Downloads 0
Medication therapy management of patients with spinal muscular atrophy during the perioperative period of scoliosis correction surgery
Spinal muscular atrophy (SMA), a devastating hereditary neuromuscular disease, is often complicated by scoliosis. While scoliosis correction surgery is frequently indicated to correct spinal deformities, it is not withou...
Advances in real-world research on disease-modifying treatments for spinal muscular atrophy
Spinal muscular atrophy (SMA) is a genetic neuromuscular disorder that leads to muscle weakness, atrophy, and which can lead to death in severe cases. Recently, therapeutic drugs that can modify SMA have emerged and have...
The effect of antineoplastic therapy on ovarian function of children and adolescents
In recent years, antineoplastic therapy have been continuously improved, and the long-term survival rate of children and adolescents with tumor has been significantly increased. Therefore, the long-term quality of life h...
Diagnosis and treatment of one case of refractory neuromyelitis optica spectrum disorder in adolescents
To preliminarily explore the feasibility and effectiveness of olfatomuzumab (OFA) in the treatment of patients with refractory neuromyelitis optica spectrum disorder (NMOSD). A 15-year-old adolescent female with seroposi...
The treatment of ALPS-like with LRBA deficiency by haploid hematopoietic stem cell transplantation: a case report
A male infant, aged 1 month and 24 days, was diagnosed with immune thrombocytopenia (ITP) and autoimmune hemolytic anemia (AIHA). Whole-exome gene sequencing revealed compound heterozygous mutations of LRBA, confirming a...