Research progress on the clinical application of esketamine

Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 12

Abstract

Esketamine is the <i>S</i>-enantiomer of racemic ketamine, which has a similar pharmacological mechanism to ketamine. Esketamine has the advantages of fast onset, fast metabolism, little impact on circulatory and respiratory functions, and strong sedative and analgesic effects. Therefore, esketamine is widely used in multidisciplinary and field areas such as psychiatric disorders, perioperative anesthesia, first aid and critical illness increasingly. This article reviews the pharmacological characteristics, mechanism of action, clinical application status and adverse reactions of esketamine, which aims to provide a reference for application and research.

Authors and Affiliations

JIANG Lele, DU Xiaoxuan

Keywords

Related Articles

Effects of individualized positive end-expiratory pressure on pulmonary function in patients undergoing thoracic surgery

Objective To evaluate the effect of setting the optimal positive end-expiratory pressure (PEEP) based on static compliance (Cstat) on pulmonary function in patients undergoing thoracic surgery. Methods Sixty patients sch...

Effects of unicondylar and total knee arthroplasty on knee osteoarthritis

<b>Objective</b> To compare the therapeutic effects of unicondylar knee arthroplasty (UKA) and total knee arthroplasty (TKA) on knee osteoarthritis (KOA) to provide references for the clinical selection of the best surg...

Expert recommendations on the utilization of sodium-glucose cotransporter 2 inhibitors for patients with type 2 diabetes in primary medical institutions

Sodium-glucose cotransporter 2 inhibitors (SGLT-2i) are increasingly utilized in the treatment of type 2 diabetes, especially for their efficacy in weight reduction and improvement of cardiovascular and renal outcomes, a...

Effects of integrated Chinese and Western medicine intervention on the recovery of gastrointestinal function after surgery in 70 patients with cardiac myxoma

Objective To investigate the efficacy of conventional treatment and nursing intervention combined with moxibustion on the recovery of gastrointestinal function in patients with cardiac myxoma. Methods A total of 70 patie...

Analysis of influencing factors on delivery mode of twin pregnancy

Objective To explore the factors affecting the mode of delivery in twin pregnancies. Methods Clinical data of 2 085 pregnant women with twin pregnancy who were delivered in the First Affiliated Hospital of Nanjing Medica...

Download PDF file
  • EP ID EP753618
  • DOI 10.13429/j.cnki.cjcr.2024.12.039
  • Views 8
  • Downloads 0

How To Cite

JIANG Lele, DU Xiaoxuan (2024). Research progress on the clinical application of esketamine. Chinese Journal of Clinical Research, 37(12), -. https://europub.co.uk/articles/-A-753618