Research progress on the correlation between imaging markers and cognitive dysfunction in cerebral small vessel disease
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 4
Abstract
Some patients with cerebral small vessel disease (CSVD) may experience cognitive decline and may progress to dementia, which seriously impairs the quality of life of patients. Current studies on the correlation between CSVD imaging markers and cognitive impairment have shown that the distribution and severity of white matter hyperintensity (WMH), enlarged perivascular spaces (EPVS), cerebral microbleeds (CMB), and lacunar infarction (LI) have different effects on various cognitive domains. The cognitive dysfunction caused by CSVD may be related to indirect effects of inflammatory factors and damage to the brain tissue fiber bundles. However, the relationship between CSVD imaging markers and cognitive function and its related mechanisms still need to be further studied and verified.
Authors and Affiliations
Nan XING, Suyu HUA, Litao. LI
Keywords
Related Articles
- EP ID EP750481
- DOI 10.3969/j.issn.1002-0152.2024.04.009
- Views 1
- Downloads 0
Clinical characteristics of late-life depression patients with venous thromboembolism in the elderly ward
[Objective] To analyze the clinical characteristics and related to risk factors of late-life depression patients with venous thromboembolism in the elderly ward. [Methods] A retrospective analysis was conducted on 143 ho...
Research progress on brain structure and function in patients with major depressive disorder after modified electroconvulsive therapy
Modified electroconvulsive therapy (MECT) has a good therapeutic effect on major depressive disorder (MDD), but its mechanism of action is still unclear. In recent years, accumulated studies have confirmed the effects of...
Clinical characteristics of 30 patients with intracranial hypotension syndrome
[Objective] To analyze and summarize the clinical presentation of spontaneous and secondary intracranial hypotension syndrome(IHS). [Methods] Patients diagnosed with spontaneous or secondary IHS from September 2022 to Ma...
Investigating the distant thalamic and substantia nigra damage in patients with cerebral infarction based on voxel morphology analysis
[Objective] To explore the clinical values of voxel-based morphometry (VBM) analysis in magnetic resonance imaging (MRI) for detecting secondary damage to the distant thalamus and substantia nigra in patients with cerebr...
Progress in the study of insomnia and its non-drug treatment in relation to heart rate variability
Heart rate variability (HRV) is an important indicator of autonomic nervous system function, reflecting the dynamic balance of autonomic regulation. Reviewing the effects of insomnia on HRV and the potential effects of n...