Research progress on the correlation between imaging markers and cognitive dysfunction in cerebral small vessel disease
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 4
Abstract
Some patients with cerebral small vessel disease (CSVD) may experience cognitive decline and may progress to dementia, which seriously impairs the quality of life of patients. Current studies on the correlation between CSVD imaging markers and cognitive impairment have shown that the distribution and severity of white matter hyperintensity (WMH), enlarged perivascular spaces (EPVS), cerebral microbleeds (CMB), and lacunar infarction (LI) have different effects on various cognitive domains. The cognitive dysfunction caused by CSVD may be related to indirect effects of inflammatory factors and damage to the brain tissue fiber bundles. However, the relationship between CSVD imaging markers and cognitive function and its related mechanisms still need to be further studied and verified.
Authors and Affiliations
Nan XING, Suyu HUA, Litao. LI
Emergency single drainage tube and dual target thalamic hematoma ventricular drainage surgery based on body surface marker localization for the treatment of thalamic hemorrhage breaking into the ventricle with hydrocephalus
[Objective] To explore the application value of emergency temporal body surface positioning for single drain dual-target thalamic hematoma ventricular drainage in the treatment of thalamic hemorrhage breaking into ventri...
Research on the effects of NSUN2 gene knockout on the differentiation and apoptosis of PC12 cells
[Objective] To investigate the role of the NOP2/Sun RNA methyltransferase 2 (NSUN2) gene in functions such as differentiation and apoptosis in PC12 cells, with the aim of exploring the function of the NSUN2 gene in nervo...
A case of glycogen accumulation disease typeⅡ
A case of glycogen accumulation disease type Ⅱ was reported. The patient was a 26-year-old male who presented with skeletal muscle atrophy and weakness of limbs and myocardial involvement in his youth. Laboratory and pat...
The clinical value of visual evoked potential in assessing visual pathway of visual hallucinations in Parkinson disease
[Objective] This research was to evaluate the integrity of visual pathways in patients with Parkinson disease (PD) by visual evoked potential (VEP), especially those with visual hallucinations. [Methods] A total of 76 PD...
Molecular basis underlying gray matter volume changes in patients with AIWG: a transcriptome-neuroimaging study
[Objective] To investigate the gray matter volume (GMV) changes and molecular basis underlying antipsychotic-induced weight gain (AIWG). [Methods] One hundred twenty-nine first-episode schizophrenia patients from October...