Research progress on the mechanism of non-alcoholic fatty liver disease caused by hepatic insulin resistance
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 7
Abstract
Non-alcoholic fatty liver disease (NAFLD) refers to a clinicopathological syndrome characterized by macrovesicular steatosis and lipid accumulation of hepatocytes, except for alcohol and other specific factors associated with liver damage. In terms of etiology, NAFLD is highly correlated with hepatic insulin resistance (IR). Elucidation of the pathogenesis of hepatic IR is expected to provide theoretical support for drug research in NAFLD. Therefore, this article reviews the research progress on the mechanism of NAFLD caused by hepatic IR.
Authors and Affiliations
ZHANG Ruonan, HE Junhua
Effect of blood lactate clearance rate on the prognosis of sepsis patients undergoing continuous renal replacement therapy
Objective To analyze the blood lactate levels and lactate clearance rate in septic patients undergoing continuous renal replacement therapy (CRRT) with different clinical outcomes, and to explore the value of blood lact...
Clinical efficacy of robotic pancreaticoduodenectomy in treatment of periampullary carcinoma
"<b>Objective</b> To investigate the clinical application and efficacy of Da Vinci robotic assisted pancreaticoduodenectomy (RPD) in treatment of periampullary carcinoma(PAC). <b>Methods</b> The clinical data of 8...
Effect of subanesthetic dose of esketamine on perioperative hemodynamics in patients undergoing lumbar surgery under general anesthesia
Objective To analyze the effect of subanesthetic dose of esketamine on perioperative hemodynamics and adverse events in patients undergoing lumbar spine surgery under general anesthesia. Methods The clinical data of 70...
Research progress of left bundle branch block
Left bundle branch block (LBBB) is an important cause of heart failure. When LBBB occurs, the excitation sequence of the left ventricle changes, leading to the change of cardiac systolic pattern, resulting in cardiac ele...
Effect of <i> Porphyromonas gingivalis </i> up-regulating Src protein expression on proliferation, migration and invasion of esophageal squamous cell carcinoma
"<b>Objective</b> To investigate the effect ofPorphyromonas gingivalis ( P. gingivalis , Pg) on the proliferation and migration of esophageal squamous cell (KYSE30) through up-regulating proto-oncogene tyrosine protein...