Research progress on the pathogenesis and treatment of cervical spondylotic myelopathy
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 5
Abstract
Cervical spondylotic myelopathy (CSM) is the most serious subtype of cervical spondylosis, which is the main cause of spinal cord dysfunction in middle-aged and elderly people, and the pathogenesis of this CSM is complex, mainly including degenerative aging, dynamic instability, spinal cord ischemia, spinal cord injury, inflammation, apoptosis, and other possible mechanisms. The clinical treatment of the CSM mainly includes conservative treatment and surgical treatment, conservative treatment includes drugs, acupuncture, moxibustion, traction, physical therapy and manual treatment, surgical treatment can be divided into anterior surgery, posterior surgery, anterior and posterior combined surgery according to the surgical approach. The choice of treatment regimen should be based on the patient's symptoms, signs, and the results of auxiliary examinations, but how to choose the appropriate treatment plan is still the focus of clinicians. This article focuses on the research progress of the pathogenesis and treatment methods of this disease, in order to provide a reference for the diagnosis and treatment of cervical myelopathy.
Authors and Affiliations
LIU Lijun*, GAO Shan, MA Guangbin, LI Peng, JIA Menglong, YANG Yang, LIU Ming, YU Longtan
Relationship between immune-related markers and clinicopathological features and prognosis in patients with colorectal cancer
Objective To analyze the relationship between immune-related markers [A proliferation-inducing ligand/tumor necrosis factor superfamily 13(APRIL/TNFSF13), B lymphocyte activating factor (BAFF) and lymphocyte activating...
Influencing factors of pathological complete response in triple-negative breast cancer with neoadjuvant chemotherapy
Objective To analyze the clinical and pathological factors affecting pathological complete response (pCR) of triple-negative breast cancer (TNBC) after neoadjuvant chemotherapy (NAC). Methods A retrospective analysis wa...
Efficacy of bronchoscopic ablation combined with local injection of endostatin in advanced non-small cell lung cancer patients with intratracheal metastasis
Objective To explore the efficacy and safety of bronchoscopic ablation combined with local injection of endostatin in patients with intratracheal metastasis of advanced non-small cell lung cancer(NSCLC). Methods A retr...
Expression and significance of Toll-like receptor 5 in peripheral blood mononuclear cells of patients with rheumatoid arthritis
Objective To examine the expression levels of Toll-like receptor 5 (TLR5) on peripheral blood monocytes in patients with rheumatoid arthritis (RA), and to explore its clinical significance. Methods A total of 140 RA pat...
Efficacy of robot-assisted full-endoscopic transforaminal lumbar interbody fusion in the treatment of degree Ⅰand Ⅱ lumbar spondylolisthesis
<b>Objective</b> To evaluate the efficacy of robot-assisted full-endoscopic transforaminal lumbar interbody fusion (Endo-TLIF) in the treatment of grade Ⅰ and Ⅱ lumbar spondylolisthesis. <b>Methods</b> The clinical dat...