Research progress on the relationship between attention deficit and hyperactive disorder and inflammation
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 8
Abstract
The pathogenesis of attention deficit and hyperactive disorder (ADHD) remains unclear. Evidence from epidemiological, biomarker, and genetic studies indicates that inflammation may play a crucial role in ADHD development. Inflammation can influence the onset and progression of ADHD through various mechanisms, such as activation of the hypothalamic-pituitary-adrenal (HPA) axis, alterations in neurotransmitter metabolism, maternal immune activation, disruption of the blood-brain barrier integrity, and impacts on neurodevelopment. A deeper understanding of the relationship between inflammation and ADHD could provide valuable insights into the pathophysiological mechanisms of ADHD and open new perspectives for clinical diagnosis and treatment.
Authors and Affiliations
Yongchang ZHANG, Caiyan LIU, Xiangzhen FU, Lingling SHI
Keywords
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- EP ID EP750536
- DOI 10.3969/j.issn.1002-0152.2024.08.008
- Views 24
- Downloads 0
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