Resistance in Staphylococcus Aureus: The Never-Ending Story
Journal Title: Acta Facultatis Medicae Naissensis - Year 2016, Vol 33, Issue 3
Abstract
Combating Staphylococcus aureus (S. aureus) infections using antibacterial drugs is actually an ongoing effort to overcome resistance mechanism of this microorganism. In this paper, we discussed (1) the mechanisms of resistance to some of the most commonly used antimicrobial agents in the treatment of S. aureus: methicillin, vancomicyn and quinolones. In addition, (2) efflux pump mechanisms involved in maintaining homeostasis in the presence of compounds that inhibit S. aureus growth and reproduction, as well as mechanisms of resistance to a number of antibiotics, have been reviewed.
Authors and Affiliations
Jovan Orlović, Biljana Miljković-Selimović, Marina Dinić, Ljiljana Ristić
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