Results of the Local Steroid Injections in the Simple Bone Cyst
Journal Title: Bezmiâlem Science - Year 2020, Vol 8, Issue 1
Abstract
Objective: Steroid injections represent one of the simple treatment alternatives for simple bone cysts (SBC). The aim of this study was to evaluate the results of local steroid injections in the treatment of SBC. Methods: Seventeen patients (11 males, 6 females; mean age 12.4 years; range=2 to 39 years) with SBC were treated with injection of methylprednisolone acetate (MPA) with the use of the two-needle technique. The cysts were localized in the proximal humerus (n=6), the calcaneus (one patient had bilateral lesions) (n=2), proximal femur (n=7) and the tibia (n=2). Pathological fractures occurred in three patients before steroid injection. These three patients with pathological fractures were treated with injection of MPA after fractures healed. Each patient received a maximum of four injections at eight week intervals, each consisting of 40-160 mg of MPA. The patients were followed up with plain radiographs obtained in the first month, third month, sixth month, and at the end of a year. After the first year, patients were followed up with plain radiographs once a year. The mean follow-up duration was twenty two months (range=3 to 48 months). Cyst healing was assessed according to the modified Neer classification. Results: Treatment with MPA resulted in complete recovery in ten cysts (55%) and recovery with residual lesions in three cysts (17%). Three cysts (17%) did not respond to steroid treatment and two patients (11%) developed recurrence. The results were satisfactory (72%) in patients with complete recovery and partial recovery with residual lesions, and unsatisfactory in five patients (28%). The patients with recurrence were treated with curettage and grafting or cementation. No procedure-related complications were encountered. Conclusion: Our findings suggest that, the treatment with local steroid injection in SBC provides satisfactory results, thus this treatment with low morbidity can be applied to these patients before aggressive treatment.
Authors and Affiliations
Vahdet UÇAN, Anıl PULATKAN, Ahmet Can ERDEM, Mehmet KAPICIOĞLU, Volkan GÜRKAN
Keywords
Related Articles
- EP ID EP684484
- DOI 10.14235/bas.galenos.2019.3121
- Views 176
- Downloads 0
Effect of Flavopiridol on Cell Cycle, Apoptosis and Biomolecule Structure Changes in Breast Cancer Stem Cells
Objective: Cancer stem cells (CSCs) are a small population in cancer, which are responsible for therapeutic resistance, relapse and metastasis. Flavopiridol has antitumor activity against various types of cancer cells. T...
Evaluation of the Effectiveness of Simulation and Web Based Training Methods in the Development of Knowledge and Skills of Urinary İncontinence Management in Nursing Students
Objective: The aim of this study was to evaluate the effectiveness of simulation and web based training methods in developing knowledge and skills of urinary incontinence (UI) management in nursing students. Methods: Th...
Comparison of Intravenous, Intra-articular, and Combined Tranexamic Acid Use in Primary Total Knee Arthroplasty without a Tourniquet and a Drain
Objective: We assessed the effect of tranexamic acid (TXA) route of administration on the estimated blood loss (EBL) in patients undergoing primary total knee arthroplasty (TKA) without tourniquet and drain use. Methods...
The Effects of Spinopelvic Parameters Such As Lumbar Lordosis and Sacral Slope Angles in the Development of Lumbar Disc Degeneration
Objective: Spinopelvic parameters were identified and the association between sagittal spinopelvic alignment and lumbar disc diseases have been reported in several studies. The purpose of this study was to evaluate the s...
Development and Validation of an In Vitro Dissolution Method Based on HPLC Analysis for L-Dopa Release From PLGA Nanoparticles
Objective: In the past decade, dissolution testing has emerged as a valauble tool for the characterization of drug product performance in the field of pharmaceuticals. During the development of new formulations, dissolut...