RETINOBLASTOMA AND ITS CLINICOPATHOLOGICAL CORRELATION AT A TERTIARY CARE CENTRE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 72
Abstract
BACKGROUND Retinoblastoma is the commonest childhood primary malignant intraocular neoplasm that is often characterised by spontaneous regression. They display photoreceptor differentiation. This study provides the clinical presentations and histological profiles of retinoblastoma in a tertiary care centre in Chhattisgarh State, in Central India. MATERIALS AND METHODS A retrospective study of clinically and histologically verified retinoblastoma at Pt JNM Medical College, Raipur, Chhattisgarh from January 2010 to December 2011 was undertaken. The clinical and histological features were analysed using the patient’s case folder and surgical pathology records. RESULTS There were 50 patients, 32 males and 18 females (M:F ratio 1.7:1), age range from 5½ months to 6 years with 42 eyeball tumours histologically confirmed retinoblastoma during the study period. Proptosis with chemosis was the most common clinical presentation (76.1%). Bilaterality was 15% in this study. Enucleation and Exenteration combined with chemotherapy were offered to 31 (75%) and 11(25%) patients respectively. CONCLUSION Moderately differentiated type with extensive areas of tumour necrosis was the commonest histological pattern. 27 (65%) of the patients died before completing the course of chemotherapy
Authors and Affiliations
Shruti Chandrakar, Ashok Kumar C
Keywords
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- EP ID EP265541
- DOI 10.14260/jemds/2017/1104
- Views 87
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