Retrospective Analysis of Patients with Sternum AsA Site of Recurrence in Treated Cases of Carcinoma Breast and Effect of Palliative Therapy-ASingle Cancer Centre Experience.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Background: Bone metastasis is a frequent complication of cancer. It occurs in up to 70% of patients with advanced breast cancer. Sternal involvement in patients with breast cancer is relatively rare and its treatment is still controversial. The present retrospective analysis aims to bring forth the role of palliative treatment (radiotherapy and chemotherapy) in this unusual site of bony recurrence. Material & methods: Data of pre-treated carcinoma breast patients from Nov 2012- Nov 2013 who had histopathologically proven sternal site recurrence and had received palliative treatment (radiotherapy & chemotherapy) were considered for analysis. Response to palliative radiotherapy and chemotherapy was assessed using RECIST criteria version 1.1, whilepain was assessed using pre and post treatment VAS score. Result: 9 patients with sternum as site of metastasis were detected. Post RT 7/9 (77.77%) patients had partial response while 2/9 (22.22%) patient had negligible response. 2/9 (22.22%) patients after completion of palliative radiation and chemotherapy treatment had complete response,6/9 (66.66%) had partial response and 1 had stable disease. All 9 patients were found to be having moderate response to pain, assessed 1 month after completion of treatment. Conclusion: Sternal metastasis to a certain extent can be taken care of with the palliative treatment and supportive care but the exact etiopathogenesis, prevention protocols and definitive modality of treatment still needs to be explored and discussed.
Authors and Affiliations
Divyesh Kumar
Keywords
Related Articles
- EP ID EP590900
- DOI 10.9790/0853-1601108287.
- Views 31
- Downloads 0
Clinical Study to Compare the Efficacy of Platelet Rich Plasma versus Conventional Dressing in Chronic Non-Healing Ulcers
Chronic Wounds Are A Major Health Challenge And Are A Growing Socioeconomic Problem All Over The World. The Goal Of Wound Care In Chronic Ulcers Is To Facilitate Healing Using Standardized Protocols Of Wound Care. The Ma...
A 4 Month Male Child With Sacrococcygealneuroblastoma: A Case Report.
Neuroblastoma is the most common extracranial solid tumor of childhood. Sacrococcygealneuroblastomas are reported to be rare. We report a case of a poorly-differentiated neuroblastoma case, detected in a 4-month-old male...
Research Effect on Blood Glucose Level After Injection of Lignocaine with Adrenaline (Original Research)
Introduction: The injection of local anesthesia with adrenaline in oral surgical procedures is associated with the metabolic changes in blood glucose level.The present paper aims to study the changes in blood glucose lev...
The Nutritional status of preschool children in urban and rural areas of Benin City, Edo State
The nutritional status of preschool children in urban and rural areas of Benin City, Edo State was investigated. Preschool children aged between 3 and 5 years were selected from nursery schools in urban (n= 150) and rura...
Imaging Prescription Patterns Among Dentists
To our knowledge, there are no data in the English literature to characterize the pattern of prescribing images among dentists. Therefore, we surveyeddentists to determine their habits when requesting images for their pa...