Retrospective Analysis of Tumor Location with Residue Rates in High-grade Glial Tumors
Journal Title: European Archives of Medical Research - Year 2020, Vol 36, Issue 2
Abstract
Objective: Glioblastoma is the most commonly seen and quite an aggressive type of primary brain tumor. Location of the tumor, age, and sex are important prognostic factors. The aim of this study was to present the retrospective data about glioblastoma patients in which location of glioblastoma and calculation of residual tumor tissue was performed at our clinic. Methods: Tumor location, age and sex distributions, and residue presence in control magnetic resonance imaging (MRI) of 99 patients treated at our clinic within the last two years with a high-grade glial tumor were examined retrospectively. Variables included in the analysis were demographic data and the presence of residue on the control MRI within 24 hours. Chi-square test was used for comparisons. The data were analyzed by SPSS version 24.0 package program. Results: Of a total of 99 glioblastomas, the male/female ratio was 2:1, the average age of the patients was 54±37 (minimum: 18, maximum: 88; standard deviation: 15.08). In MRI, tumor was located at the frontal and temporal lobes with maximal percentile. In 55 of the cases, total resection was seen. In 38 of the cases, residue under 10% was seen, and in 6 of the cases, residual mass over 10% was seen. Relationship of tumor location with residual mass was not statistically significant (p=0.562). Conclusion: The aim of neurosurgery in glioblastomas is surgical excision to remove as much tumor as possible with minimal neurological deficit. Preoperative characterization of the tumor through current imaging methods makes a significant contribution to mortality and morbidity. New prognostic parameters are needed based on new surgical approaches and imaging techniques.
Authors and Affiliations
Mehmet Hakan Seyithanoğlu, Tolga Turan Dündar, Serkan Kitis, Anas Abdallah, Erdinç Özek, Meliha Gündağ Papaker
Keywords
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