RETROSPECTIVE ANALYSIS OF UTERINE CARCINOSARCOMA FROM A TERTIARY CARE CENTRE IN SOUTH INDIA
Journal Title: International Journal Of Advances In Surgery - Year 2019, Vol 3, Issue 3
Abstract
Background: Uterine Carcinosarcoma (UCS) is a highly aggressive, rare, biphasic tumour. The study was retrospectively conducted to analyse the clinical profile, treatment and outcomes of uterine carcinosarcoma cases presenting to a tertiary care centre. Methods: In this retrospective study, the clinical characteristics, treatment and outcomes of all patients with uterine carcinosarcoma was evaluated. The study was conducted in a tertiary care hospital, Chennai, India between January 2014 to December 2018. The data was collected from the case records of the eligible participants onto a structured proforma. Demographic, clinical, staging, treatment and its outcomes were the variables of interest for analysis. Results: A total of 18 subjects were included in the final analysis. The mean age of the participants was 58.72 ± 8.39 years. Fourteen(77.78%) participants had BMI <30. Seventeen (94.44%) of study participants were post-menopausal. Ten(55.56%) presented with bleeding, Fifteen(83.33%) with pain and Three (16.67%) with abdominal mass. Sixteen (88.89%) had >50% myometrial invasion. Nine (50%) participants underwent staging LAP/TAH/BSO/omentectomy/lymph node dissection, Four(22.22%) underwent with Radical hysterectomy, Four(22.22%) underwent debulking surgery. Among study population, Six(37.50%) received carboplatin + paclitaxel and Four(22.22%) had adjuvant RT. This study shows overall mortality was 44.44%. Median duration of survival was 16 months (95%CI 3.15 to 28.84) among the study population Conclusions: Uterine carcinosarcoma is a rare tumour, often diagnosed at an advanced stage. Because of its rarity, its profile cannot be generalized to the entire population.
Authors and Affiliations
Dr. Manivannan. P, Dr. Kalaichelvi. K, Dr. Suresh kumar. S, Dr. Raja. G
Keywords
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