Retrospective observational study of antimicrobial drugs utilization in medical ICU in a tertiary care teaching hospital of Himachal Pradesh
Journal Title: IP International Journal of Comprehensive and Advanced Pharmacology - Year 2017, Vol 2, Issue 3
Abstract
Introduction: Patients admitted in Intensive Care Units (ICUs) are already sick and they are vulnerable to superadded infections. They suffer from other co-morbidities and also undergo invasive procedures. So these patients are under cover of antimicrobial drugs. Materials and Method: It was a retrospective observational study, conducted during a period from March, 2016 to July, 2016. Data of 152 patients was collected from the Central Record Section of the hospital. Drug utilization pattern of antimicrobial agents was analyzed. Results: Out of 152 patients, 100 (65%) were males and 52 (35%) were females. The mean age was 60.05 ± 16.05 years with a range of 20 - 90 years. The mean age of males was 58.72 ± 14.85 years and females were 62.52 ± 17.80 years. Average duration of hospital stay was 2.96 ± 2.57 days with a range of 1 to 20 days. Total of 131 antibiotics were prescribed. Antibiotics prescribed were 3rd generation cephalosporins in 43 patients, macrolides in 27 patients, quinolones in 9, antianaerobics in 8, tetracycline in 5, oxazolidinones, aminoglycosides, antifungals and others in 2 patients each. FDCs were prescribed in 24% prescriptions. Prescription pattern of FDCs was piperacillin + tazobactam in 20 patients, amoxicillin + clavulanic acid in 5 patients, ceftriaxone + sulbactam in 3 patients, polymyxin B + bacitracin + neomycin in 2 patients and ofloxacin + ornidazole in 1 patient. Conclusion: Drug utilization studies provide us prescription pattern in the medical ICU. We can minimize the incidence of antimicrobial resistance by following the standard guidelines of antimicrobial prescription.
Authors and Affiliations
Arvind Kumar, Dinesh Kansal, Usha Kumari Chaudhary
Keywords
Related Articles
- EP ID EP319513
- DOI 10.18231/2456-9542.2017.0005
- Views 60
- Downloads 0
Study on in- vitro antidiabetic potential of stem part of Musa paradisiaca Linn
The study proposed to evaluate the Phytochemical and in-vitro antidiabetic potential of the stem part of Musa paradisiaca Linn. Musa paradisiaca is commonly known as banana. Its fruit is generally used as dietary source....
Carbamazepine induced secondary hyperparathyroidism: A rare clinical entity
Antiepileptic drugs (AEDs) are associated with altered bone metabolism and decreased bone density thereby increasing the risk of fractures several folds. This is a unique case report of a young 34 year old female diagnos...
Evaluation of diuretic activity of Lagenaria Siceraria in Albino rats
Lagenaria siceraria belongs to Cucurbitaceae family. It is commonly known as lauki (Hindi) and bottle gourd (English) is a medicinal plant. It is used as medicine for its cardio tonic, general tonic and diuretic properti...
Study of invitro antimicrobial activity of biogenically synthesised silver nanoparticle using leaf extract of aponogeton natans
Different biological methods are gaining recognition for the synthesis of silver nanoparticles (Ag-NPs) due to their multiple applications. One of the most important applications of Ag-NPs is their use as an antibacteria...
Synthesis & Evaluation of isoxazole for their antimicrobial activity
Isoxazole is five membered heterocyclic ring having a broad spectrum of pharmacological activities like anti-tubercular, anti-cancer, anti-bacterial, anti-fungal, anti-HIV, anti-inflammatory and anti-hypertensive activit...