Retrospective observational study of antimicrobial drugs utilization in medical ICU in a tertiary care teaching hospital of Himachal Pradesh
Journal Title: IP International Journal of Comprehensive and Advanced Pharmacology - Year 2017, Vol 2, Issue 3
Abstract
Introduction: Patients admitted in Intensive Care Units (ICUs) are already sick and they are vulnerable to superadded infections. They suffer from other co-morbidities and also undergo invasive procedures. So these patients are under cover of antimicrobial drugs. Materials and Method: It was a retrospective observational study, conducted during a period from March, 2016 to July, 2016. Data of 152 patients was collected from the Central Record Section of the hospital. Drug utilization pattern of antimicrobial agents was analyzed. Results: Out of 152 patients, 100 (65%) were males and 52 (35%) were females. The mean age was 60.05 ± 16.05 years with a range of 20 - 90 years. The mean age of males was 58.72 ± 14.85 years and females were 62.52 ± 17.80 years. Average duration of hospital stay was 2.96 ± 2.57 days with a range of 1 to 20 days. Total of 131 antibiotics were prescribed. Antibiotics prescribed were 3rd generation cephalosporins in 43 patients, macrolides in 27 patients, quinolones in 9, antianaerobics in 8, tetracycline in 5, oxazolidinones, aminoglycosides, antifungals and others in 2 patients each. FDCs were prescribed in 24% prescriptions. Prescription pattern of FDCs was piperacillin + tazobactam in 20 patients, amoxicillin + clavulanic acid in 5 patients, ceftriaxone + sulbactam in 3 patients, polymyxin B + bacitracin + neomycin in 2 patients and ofloxacin + ornidazole in 1 patient. Conclusion: Drug utilization studies provide us prescription pattern in the medical ICU. We can minimize the incidence of antimicrobial resistance by following the standard guidelines of antimicrobial prescription.
Authors and Affiliations
Arvind Kumar, Dinesh Kansal, Usha Kumari Chaudhary
Keywords
Related Articles
- EP ID EP319513
- DOI 10.18231/2456-9542.2017.0005
- Views 68
- Downloads 0
Polyvalent Anti Snake Venom: Adverse drug reactions in children
Snakebite is one of the important causes of mortality in our country. Anti-snake venom (ASV) is administered in the management of snake bite. In India polyvalent ASV is used. There is risk of anaphylactic reaction. It sh...
Proton pump inhibitor use and its relation to serum magnesium levels among hemodialysis patients: A single centre study in a South Indian tertiary care hospital
Introduction Proton pump inhibitors PPI are commonly used in clinical practice for various indications such as gastritis peptic ulcer and gastroesophageal reflux disease In Observational studies Hypomagnesaemia has been...
To analyze the variations in cost of Anti-glaucoma eye preparations available in Indian market
Aim To analyze the percentage cost variations among different brands of the commonly prescribed antiglaucoma drugsMaterial and Methods The maximum and minimum price of each brand of the drug in INR was noted by using CIM...
Retrospective pharmacoeconomic evaluation of two types of cataract surgeries in a private hospital: cost effectiveness analysis
Objective: Cataract surgery is performed by two methods; small incision cataract surgery (SICS) and topical phacoemulsification (TPE) with intraocular lens (IOL) implantation. SICS is a widely used method but technologic...
Synthesis & Evaluation of isoxazole for their antimicrobial activity
Isoxazole is five membered heterocyclic ring having a broad spectrum of pharmacological activities like anti-tubercular, anti-cancer, anti-bacterial, anti-fungal, anti-HIV, anti-inflammatory and anti-hypertensive activit...