Retrospective study of papulonodular skin lesions and their clinopathological correlation

Journal Title: International Journal of Medical Science and Public Health - Year 2015, Vol 4, Issue 5

Abstract

Background: Papulonodular lesion of the skin is a more common variety. Various types of diseases manifested with papulonodular lesions surface, for example, infectious diseases, benign neoplastic diseases, and malignant tumors as well as metastatic tumors. Therefore, a brief idea about the clinical history, age, sex, and various sites of lesion is important. Objectives: To evaluate the incidence of different infectious, benign, and malignant diseases manifested with papulonodular lesions. To study the various papulonodular lesions of skin in relation to different age group, sex, and location. To compare our observation with that of other authors and to correlate clinical data with that of histopathological study. Materials and Methods: In the present study, from November 2007 to November 2009, total 75 cases of papulonodular lesions were taken for study from Department of Dermatology and Department of Pathology, BJ Medical College and Civil Hospital, Ahmedabad, Gujarat, India. All lesions were studied with respect to clinical history, physical examination, histopathological examination of biopsy material on HE stain and also on special stains when required. Results: In the present study, 69% of papulonodular lesions of skin were of infectious origin followed by 24% as benign origin and 7% as malignant origin. In infectious lesions, most common is leprosy with incidence of 22.67%, erythema nodosum leprosum 20%, and cutaneous tuberculosis mostly scrofuloderma 8% and Prurigo Nodularis 6.67%. In benign lesions, trichoepithelioma has incidence of 8% and syringoma 5.33%. In malignant lesions, Basal cell carcinoma has incidence of 4% and metastatic carcinoma 2.67%. Clinically, most of infectious lesions are diagnosed and are con - firmed by histopathology. In leprosy, clinopathological correlation is 94.12% and in erythema nodosum leprosum, it is 93.33%, while in cutaneous tuberculosis, actinomycosis, and epidermoid cyst, clinopathological correlation is 100% with histopathological diagnosis. Conclusion: Papulonodular lesion of skin is clinically well diagnosed and better correlated with histopathological examination.

Authors and Affiliations

Rupali Patil, Mehul Makdani, Asha Gunjalia, Karan Gandhi, Harshid Patel

Keywords

Related Articles

 The effect of stretching exercise on primary dysmenorrhea in adult girls

 Background: Primary dysmenorrhea is a difficult menstrual flow in the absence of any pelvic pathology where pain is spasmodic in character and felt mainly in the lower abdomen. Women that participated in sports ex...

International Journal of Medical Science and Public Health 

 Giant cell tumor of tendon sheath is a benign soft tissue lesion most commonly found in the flexor aspect of the hand and wrist. Being uncommon in the foot and ankle, the unusual appearance of this lesion can at t...

Evaluation of effectiveness of intravenous iron sucrose in antenatal patients of iron deficiency anemia

Background: Iron deficiency anaemia (IDA) is the most common nutritional deficiency in pregnancy. Prophylactic oral iron is recommended during pregnancy to meet the increased requirement of iron. In Ind...

A study on the effect of smokeless tobacco on oral cancer done in a Tertiary Care Hospital in Southern India

Background: Oral cancer is a major problem in India. The incidence is 10.1 cases per lac for males and 4.3 per lac in females. The risk factors for the development of oral cancers include smokeless tobacco. Objectives: T...

A study of 150 cases of intraperitoneal tuberculosis

Background: Tuberculosis caused by Mycobacterium tuberculosis is a disease of great antiquity and for a long time it has maintained its evil reputation and being one of the greatest killer diseases of mankind. Th...

Download PDF file
  • EP ID EP89996
  • DOI 10.5455/ijmsph.2015.20112014123
  • Views 145
  • Downloads 0

How To Cite

Rupali Patil, Mehul Makdani, Asha Gunjalia, Karan Gandhi, Harshid Patel (2015). Retrospective study of papulonodular skin lesions and their clinopathological correlation. International Journal of Medical Science and Public Health, 4(5), 612-616. https://europub.co.uk/articles/-A-89996