Reversible myelofibrosis due to severe Vitamin D deficiency rickets
Journal Title: Medical Journal Armed Forces - Year 2018, Vol 74, Issue 4
Abstract
Myelofibrosis is an uncommon condition in infants with very few cases of reversible myelofibrosis reported in literature.1 Vitamin D deficiency (VDD) rickets is a rare but well-defined cause of this condition. With a reported recent increase in prevalence of VDD among exclusively breast fed infants and identification of newer roles of Vitamin D in modulation of hematopoiesis and immune regulation, this assumes importance. 2 In this report, we describe a 10-month-old rachitic infant with anemia and hepatosplenomegaly secondary to marrow fibrosis whose clinical features improved after Vitamin D therapy.
Authors and Affiliations
Kannan Venkatnarayan
Keywords
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- EP ID EP654101
- DOI 10.1016/j.mjafi.2017.08.004
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