Reversible myelofibrosis due to severe Vitamin D deficiency rickets
Journal Title: Medical Journal Armed Forces - Year 2018, Vol 74, Issue 4
Abstract
Myelofibrosis is an uncommon condition in infants with very few cases of reversible myelofibrosis reported in literature.1 Vitamin D deficiency (VDD) rickets is a rare but well-defined cause of this condition. With a reported recent increase in prevalence of VDD among exclusively breast fed infants and identification of newer roles of Vitamin D in modulation of hematopoiesis and immune regulation, this assumes importance. 2 In this report, we describe a 10-month-old rachitic infant with anemia and hepatosplenomegaly secondary to marrow fibrosis whose clinical features improved after Vitamin D therapy.
Authors and Affiliations
Kannan Venkatnarayan
Keywords
Related Articles
- EP ID EP654101
- DOI 10.1016/j.mjafi.2017.08.004
- Views 51
- Downloads 0
Molecular detection of blaNDM-1 (New Delhi metallobetalactamase-1) in nosocomial Enterobacteriaceae isolates by nested, multiplex polymerase chain reaction
Background: Carbapenems are considered ‘‘drugs of last resort’’ in many life-threatening infections. Advent of carbapenemases like KPC, OXA-48, VIM, IMP, and NDM have greatly affected the efficacy of these drugs, posing...
MR Geyser Sign in chronic rotator cuff tears
Acromio-clavicular (AC) joint cysts are rare presentation of chronic shoulder pathology. These cysts may be observed secondary to either degenerative changes in the AC joint with an intact rotator cuff (type 1 cyst) or f...
Evaluation of Microscopic observation drug susceptibility (MODS) assay as a rapid, sensitive and inexpensive test for detection of tuberculosis and multidrug resistant tuberculosis
Background: Microscopic observation drug susceptibility (MODS) assay has been suggested as a low cost method for rapid, accurate detection of tuberculosis (TB) and multidrug resistant tuberculosis (MDR-TB). Methods: A to...
Scrub typhus strikes back: Are we ready?
Scrub typhus has struck back, albeit with renewed vigour, impacting areas with previously known endemicity as also impressing newer expanses. It is not surprising, therefore, that Scrub typhus has emerged as a leading ca...
Intracranial hypotension: An uncommon entity with common presentation
Headache disorders are among the most common presenting complaints in any neurology outpatient department. International Headache Society classifies headaches as ‘‘primary’’ or ‘‘secondary’’. The causes of secondary head...