Review of Pathophysiological Aspects and Risk Factors for Liver Dysfunction

Journal Title: Archives of Clinical Gastroenterology - Year 2016, Vol 2, Issue 3

Abstract

The liver is accountable for many critical functions within the body and loss of those functions can cause significant damage to the body. Liver disease is a extensive term that covers all aspects that cause the liver to fail to perform its proper functions. Acute liver failure indicates the development of severe acute liver injury with impaired synthetic function without preexisting of clinical liver disease. However, chronic liver disease is characterized by destruction of the hepatic tissue. Early changes, such as fatty liver can progress via inflammation and fibrosis to cirrhosis. The main causes for liver dysfunction include dyslipidemia, obesity, viral and parasitic infection, drugs and environmental pollution, alcohol abuse, autoimmunity, and genetic defective such as hemochromatosis. The present review almost covers all the previous aspects that lead to liver dysfunction.

Authors and Affiliations

El-Din M Omar Hossam, Omar Omnia HM, Badr Gamal

Keywords

Related Articles

Percutaneous choledocho-duodenal shunt for malignant biliary obstruction

We developed a new method: percutaneous choledocho-duodenal shunt (PCDS) for complete biliary obstruction patient. At first, percutaneous transhepatic cholangio drainage (PTCD) is performed as usual manner with local ane...

Laparoscopic treatment of Biliary Peritonitis due to Double Organ injury after Swallowing of Chicken Bone

A 52 years old woman presented to emergency service after eating chicken meat few days before that. She had upper abdominal pain, vomiting, weakness and fever of 38C°. A control abdominal CT scan showed linear 50 mm fore...

ABO-incompatible living donor liver transplantation in a patient with a history of platelet transfusion-related anaphylaxis

Anaphylaxis and severe allergic transfusion reactions (ATR) are uncommon complications after blood transfusion. Nevertheless, these complications are associated with very severe outcomes, such as dyspnea, shock, and deat...

Analysis of Indications and Results of Anorectal Manometry in Two Tertiary Hospitals in India

The anorectum plays an important role in regulation of defecation and in maintenance of continence [1]. The most widely used test for anorectal function is anorectal manometry. It measures pressures of the anal sphincter...

More Pronounced Reduction of Gut Bacteria in Crohn’s Disease than Ulcerative Colitis may have just Reflected Intimate Connection Rather than Difference of these two Diseases-A Different View on Findings Published in Gut

I read with great interest a paper published recently in Gut [1], as its finding that patients with Crohn’s disease (CD) have more pronounced reduction and dysbiosis in gut bacteria than ulcerative colitis (UC) is just a...

Download PDF file
  • EP ID EP325573
  • DOI 10.17352/2455-2283.000025
  • Views 56
  • Downloads 0

How To Cite

El-Din M Omar Hossam, Omar Omnia HM, Badr Gamal (2016). Review of Pathophysiological Aspects and Risk Factors for Liver Dysfunction. Archives of Clinical Gastroenterology, 2(3), 69-76. https://europub.co.uk/articles/-A-325573