REVIEW ON BUCCUL PATCHES AS A NOVEL DRUG DELEVERY SYSTEM
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2019, Vol 8, Issue 10
Abstract
Buccal drug delivery systems relate with the mucus layer casing the mucosal epithelial superficial, and mucin molecules and rise the residence time of the dosage form at the location of absorption. The objective of this article is to review buccal drug delivery talk over the structure and environment of the oral mucosa and methodology in evaluating buccal formulations. This review also places of interest in a brief description of advantages, limitations of buccal drug delivery. The drugs which have native action or those which have extreme absorption in gastrointestinal tract (GIT) need to increased period of stay in GIT. Thus, buccal dosage forms are advantageous in enhancing the drug plasma concentrations and also therapeutic activity. Buccal Patches are the type of drug formulation that has normally a different way of administration through the buccal mucosa for drug delivery. These patches have a tendency to assistance drug enter directly the systemic circulation fugitive hepatic first pass metabolism.
Authors and Affiliations
Dr. Bhupendra M. Mahale
Keywords
Related Articles
- EP ID EP669483
- DOI -
- Views 159
- Downloads 0
NEW REAGENT FOR SPECTROPHOTOMETRIC DETERMINATION OF METFORMIN IN PURE FORMS AND IN PHARMACEUTICAL FORMULATIONS
An accurate, simple, fast and cheap spectrophotometric method has been developed for the determination of Metformin in pharmaceutical pure and dosage forms The method is based on the formation of violel complexe between...
REVIEW ON RUTA GRAVEOLENS
Bioassay-directed isolation of antifungal compounds from an ethyl acetate extract of Ruta graveolens leaves yielded two furanocoumarins, one quinoline alkaloid, and four quinolone alkaloids including a novel compound, 1-...
USE OF EMDOGAIN PROTEIN IN TREATMENT OF CHRONIC PERIODONTITIS
This study evaluated the efficacy of Emdogain enamel matrix proteins as a regenerative material in interproximal vertical defects both clinically and radiographically. Patients aged 18 to 45 years and diagnosed with chro...
INVESTIGATION OF GASTRORETENTIVE DRUG DELIVERY SYSTEM
Gastroretentive Drug Delivery System, comprising mainly of floating, bioadhesive and swellable systems have emerged as an efficient means of enhancing the bioavailability and controlled release delivery of drugs exhibiti...
BIOCHEMICAL AND PATHOPHYSIOLOGICAL ASPECTS OF THE TREATMENT OF HEPATIC ENCEPHALOPATHY IN RATS
Hepatic encephalopathy (HE) represents a diverse spectrum of complex neuropsychiatric disturbance resulting from liver disease and its concomitant metabolic and immunologic derangements. Hyperammonemia and inflammation c...