Rhabdomyolysis due to Lamivudine administration in acute viral hepatitis B infection: a case report from Malaysia
Journal Title: Electronic Physician - Year 2014, Vol 6, Issue 3
Abstract
Rhabdomyolysis is a serious but rare side effect of Lamivudine treatment. Therefore, appropriate biochemical monitoring should be undertaken when it is used in the treatment of hepatitis B. This paper presents a case of Lamivudine-associated rhabdomyolysis in a 31-year-old man with congenital heart disease and hepatitis B. Three days after starting Lamivudine, the patient developed myalgia. Significant muscle tenderness and swelling of the upper and lower limbs was discovered during a physical examination. Creatine kinase was markedly raised. Lamivudine-induced rhabdomyolysis was suspected and the drug was discontinued. Symptoms and creatine kinase activity improved within four days of Lamivudine cessation and hydration. Early identification of Lamivudine-induced rhabdomyolysis is key in preventing this potentially fatal drug reaction; withdrawal of Lamivudine may contribute to complete remission of rhabdomyolysis.
Authors and Affiliations
Janudin Baharin, Narisa Sulaiman Sahari, Sazlyna Mohd Sazlly Lim
Keywords
Related Articles
- EP ID EP88604
- DOI -
- Views 142
- Downloads 0
Corneal transplantation: A new view of life
BACKGROUND: The consequences of a corneal transplant are evaluated and classified by care providers, but understanding and interpretation of the results varies between patients, and creates different views for them and i...
Thalassemia review: features, dental considerations and management
Thalassemia is a genetic disorder that involves abnormal haemoglobin formation. The two main categories of thalassemia are alpha and beta thalassemia that are then divided into further subcategories. While some mild form...
Color doppler indices of proximal and distal parts of middle cerebral artery in fetuses with intrauterine growth restriction
INTRODUCTION: Intrauterine growth restriction (IUGR) is a major clinical issue for pregnant women. The purpose of this study was to evaluate color Doppler indices of the proximal and distal parts of the middle cerebral a...
Balanitis in Down syndrome-A case from Malaysia
This case illustrates the management by a primary care physician of a child with Down syndrome who had recurrent balanitis. Various methods of management were tried. Eventually it was just by practicing proper geni...
Surgical outcome of conjunctival rotational autograft-mitomycin C (MMC) versus free conjunctival autograft-MMC for pterygium removal: A randomized clinical trial
BACKGROUND: Pterygium is a common degenerative eye disease. Despite various surgical methods to treat pterygium, recurrence is the main complication. The main issue is finding a surgical method with the lowest recurrence...