Rhabdomyolysis due to Lamivudine administration in acute viral hepatitis B infection: a case report from Malaysia
Journal Title: Electronic Physician - Year 2014, Vol 6, Issue 3
Abstract
Rhabdomyolysis is a serious but rare side effect of Lamivudine treatment. Therefore, appropriate biochemical monitoring should be undertaken when it is used in the treatment of hepatitis B. This paper presents a case of Lamivudine-associated rhabdomyolysis in a 31-year-old man with congenital heart disease and hepatitis B. Three days after starting Lamivudine, the patient developed myalgia. Significant muscle tenderness and swelling of the upper and lower limbs was discovered during a physical examination. Creatine kinase was markedly raised. Lamivudine-induced rhabdomyolysis was suspected and the drug was discontinued. Symptoms and creatine kinase activity improved within four days of Lamivudine cessation and hydration. Early identification of Lamivudine-induced rhabdomyolysis is key in preventing this potentially fatal drug reaction; withdrawal of Lamivudine may contribute to complete remission of rhabdomyolysis.
Authors and Affiliations
Janudin Baharin, Narisa Sulaiman Sahari, Sazlyna Mohd Sazlly Lim
Keywords
Related Articles
- EP ID EP88604
- DOI -
- Views 139
- Downloads 0
The effect of personality traits on undergraduate dental students’ performance in multiple mini interviews
BACKGROUND: Multiple mini interviews (MMI) is a structured student selection method where applicants rotate around a series of stations that do not require previously learned knowledge. The Big Five Inventory (BFI) is a...
Adherence to treatment in patients with open-angle glaucoma and its related factors
INTRODUCTION: Lack of adherence to medical treatments typically lead to burdensome consequences such as progressive visual impairment, blindness, and disabilities. This study aimed to determine the adherence to medicatio...
Exploring the adaptive experiences of children with parents of myocardial infarction: A Qualitative Study
BACKGROUND: Cardiovascular diseases are the world's leading cause of mortality. These diseases are rooted in an unhealthy lifestyle. In order to confront this subject, it is essential to identify several risk factors tha...
Herbal Medicines for the Management of Irritable Bowel Syndrome: A Systematic Review
Irritable Bowel Syndrome (IBS) is a chronic digestive disorder, which is characterized by abdominal pain, bloating, diarrhea and constipation periods. The etiology is unknown. Based on the different mechanisms in the eti...
Areal location of hazardous atmospheres simulation on toxic chemical release: A scenario-based case study from Ray, Iran
BACKGROUND AND AIM: Chemical accidents cause significant danger for residents living close to chemical facilities. For this reason, this study assessed the impacts of a simulated chemical accident on surrounding resident...