Rheumatic diseases in pregnant women
Journal Title: Postępy Nauk Medycznych - Year 2010, Vol 23, Issue 5
Abstract
Rheumatic diseases often occur in young people, including women in the reproductive age. The problem of pregnancy is not so rare in this group. The main rheumatic diseases which can we find in pregnant women are: rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). The safety of pharmacotherapy in these diseases during pregnancy and lactation is very important.The most commonly used nonsteoridal anti inflammatory drugs should be used in the lowest therapeutically sufficient dose. Among the glicocorticoids, prednisone and prednisolon have the safest profile in pregnancy. Methotrexate, Cyclophosphamide and Leflunomide are contraindicated in pregnancy. The reports on the safety of the biological treatment during pregnancy are optimistic, however still not sufficient.Pregnancy in women with SLE can be complicated by preeclampsia, premature labour or miscarriage more often than in the healthy population, and it is considered a high- risk pregnancy. Symptoms of preeclampsia and SLE exacerbation are similar, so they need to be correctly differentiate.APS is associated with several pregnancy complications too. Treatment in this disease is still equivocal. Therapeutic schemes involve aspirin and heparins - preferable low molecular weight heparins. Steroids and immunoglobulins are not routinely used. Treatment in APS administrated in early pregnancy increases chances for life delivery to 80%.
Authors and Affiliations
Agnieszka Jasik, Ewa Marcinowska - Suchowierska
Keywords
Related Articles
- EP ID EP53900
- DOI -
- Views 164
- Downloads 0
Endovascular treatment of subclavian steal syndrome – own experience
Introduction. Subclavian steal syndrome (SSS) occurs when proximal part of one of the subclavian artery or brachio-cephalic trunk is significantly narrowed or obstruced. The disease is characterized by a wide range of sy...
Effectiveness of single and double predonation combined with postoperative recuperation for blood salvage in scoliosis surgery
<b>Introduction.</b> The autotransfusion is promoted for patients undergoing scoliosis surgery as a recognized mean for reducing homologous transfusion need. There is a deficiency of studies w...
Palliative care in present-day oncology
Palliative care may well be considered both the youngest and the most rapidly growing field of oncology. In its modern form it does not go back further than the 1960’s and arises directly from the works of C. Saunders an...
Analiza profilu lipidowego i stężeń glukozy na czczo wśród młodzieży warszawskiej. Zależność od uwarunkowań rodzinnych
Wstęp. Zaburzenia profilu lipidowego oraz gospodarki węglowodanowej są uważane za istotny czynnik ryzyka kardio-metabolicznego u osób dorosłych. Jednak procesy prowadzące do ujawnienia się tych chorób niejednokrotnie maj...
Badania przesiewowe w rozpoznaniu wczesnej fazy cukrzycowej choroby nerek
Wczesne rozpoznanie nefropatii cukrzycowej wydaje się być ważnym elementem diagnostyki chorych na cukrzycę. Pozwala ono na wczesne wdrożenie leczenia nefroprotekcyjnego, a co za tym idzie, zmniejszenie progresji choroby...