Rheumatoid Arthritis, Its Diagnostic Approach and How to treat it
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2022, Vol 2, Issue 04
Abstract
Introduction. Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by symmetrical erosive polyarthritis leading to progressive disability. It is more common in women, with a 3:1 ratio. Environmental risk factors are smoking, exposure to silica and textile dust. Materials and methods. Fifteen articles and three books on rheumatoid arthritis were chosen to identify the most accurate diagnostic methods and the most effective and innovative treatments. Discussion. Related autoantibodies, such as rheumatoid factors, anti-citrullinated antibodies and anti- caramylated antibodies can be found in serum long before the disease develops. The interaction between genetic and environmental factors causes a breakdown of immune tolerance and triggers systemic autoimmunity. It has been shown that the lungs, oral mucosa, and gastrointestinal tract are initial sites where the immune system can become activated and produce RA. Different imaging techniques are available for diagnosis: plain radiography, Doppler ultrasound, and magnetic resonance imaging. Doppler ultrasound was found to be more sensitive in identifying minimal synovitis and more sensitive than plain radiography in detecting joint erosions. As pharmacological treatment, it has been concluded that the first-line drug is methotrexate, as it relieves signs and symptoms, improves physical function, and prevents or slows the progression of joint damage. We also observed that NSAIDs help in the inflammatory and symptomatic control of RA. Conclusion. The quality of life of affected patients has been maintained thanks to the early detection of the disease, since there are several treatments (physical therapies, aerobic exercises, medications, etc.), which help to stop the evolution of this disease and thus allow the patient to lead a daily life.
Authors and Affiliations
María F. Calderón, Miriam G. Rodríguez, Leslie Rodríguez, María E. Pérez Santana
Keywords
Related Articles
- EP ID EP713829
- DOI 10.47191/ijmscrs/v2-i4-05
- Views 86
- Downloads 0
Diagnosis and Treatment of Weber-Christian Disease for the First Contact Physician
Weber-Christian disease is an inflammatory disease, of the lobular panniculitis group, affecting the skin, subcutaneous adipose tissue and other organs. It is characterized by recurrent episodes...
Exploring Hyaluronic Acid as a Potential Standard Dressing for Burn Wound
A massive loss of dermis layer such as in deep burn wounds brings several important consequences and complications which contribute tomajor problems, personally and economically, for theburnpa...
Diagnosis and Treatment of Pyelonephritis During Pregnancy
Urinary tract infections are the most common infections in pregnant women. The most common are asymptomatic bacteriuria, cystitis and pyelonephritis, the latter presenting as a complication in 1 to 2% of women. Urolith...
Primary Ovarian Diffuse Large B-Cell Lymphoma in a 34 year old Lady :A Case Report
Involvement of the ovary by malignant lymphoma is well known as the late manifestation of disseminated disease. Primary ovarian lymphoma(POL) is extremely rare , accounting for 0.5 % of all NHLs and 1.5% of all mal...
The Main Symptoms and Clinical Manifestations of Coronavirus Disease in Children: A Descriptive Minireview
Coronaviruses (coronaviruses) are a large family of viruses that cause diseases in both humans and animals. It is known that the emerging corona affects the respiratory system in addition to other more serious diseases s...