Rheumatoid Factor in Moroccan Patients with Systemic Lupus Erythematosus: Association with Antinuclear Antibodies and Disease Activity
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by autoantibody production. This study aims to investigate the prevalence of rheumatoid factor (RF) in SLE patients from Morocco and evaluate its correlation with antinuclear antibodies (ANA), disease activity in SLE Moroccan patients. RF was measured using ELISA in 52 SLE patients with and without arthritis. Levels ≥ 24 units/ ml defined a positive test of RF. Positive RF was detected in 21.15% % of SLE patients. The mean titer of RF in the SLE group was 71.75 U/ml. ANA) were tested by indirect immunofluorescence method .We found an increase of level of RF in patient with ANA positive. The frequency of presence of RF was higher in patients with active disease than in those with inactive. In the Moroccan population we demonstrated the presence of high titer of RF in SLE. Results from our study also identified the association between RF and disease activity in SLE patients.
Authors and Affiliations
Ouahiba Bhallil, Aicha Ibrahimi, Naima Ouzeddoun, Rabia Bayahia, Malika Essakalli
Keywords
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- EP ID EP431049
- DOI 10.9790/0853-1801046365.
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