Risk factors and features of recurrent bacterial complications of upper respiratory tract viral infections in children
Journal Title: Медичні перспективи - Year 2017, Vol 22, Issue 3
Abstract
The aim of the study was to determine risk factors for recurrent bacterial complications of the upper respiratory tract viral infection (URTI) in children, as well as the clinical and immunological features of the course of such complications. We enrolled 214 children aged 3-18 years with URTIs complicated with acute otitis media or acute bacterial rhinosinusitis. Frequency of bacterial complications of URI in 128 children was low (group I) and in 86 children it met the criteria of recurrent course (group II). In addition to the standard examination, lysozyme levels in the oropharyngeal secretion were determined three times during the disease. It was found that children of group II were characterized by an early debut of respiratory morbidity (at the age of 6.00 (4.00, 12.00) months against 13.00 (4.50, 16.00) months in children of group I (p<0,0001), as well as a longer duration of catarrhal and intoxication syndromes in similar forms of the disease. The most significant risk factors for the formation of the recurring complication pattern were maternal smoking (OR=2.73, 95% CI [1.34, 5.48]), along with gastroenterological pathology and frequent URTI in the mother and a shortened period of breastfeeding. In children with recurrent bacterial complications of URTI, there was an impaired local resistance of the upper respiratory tract mucous membranes (as a decrease in the concentrations of lysozyme) in all periods of the disease, which persisted after recovery.
Authors and Affiliations
A. V. Karpenko
Keywords
Related Articles
- EP ID EP229941
- DOI 10.26641/2307-0404.2017.3.111931
- Views 94
- Downloads 0
Analysis of disability indicators due to occupational diseases in the Lviv region: problems and perspectives of the decision
Disability is a social phenomenon that can not be ruled out by any society. The potential of society in combating the growth of disability – as a social evil – is determined not only by the degree of understanding of thi...
Гигиеническая оценка частоты потребления пищевых продуктов животного происхождения в рационе студентов-медиков и обоснование путей его коррекции
Гігієнічна оцінка частоти споживання харчових продуктів тваринного походження в раціоні студентів-медиків та обгрунтування шляхів його корекції. Єльцова Л.Б., Омельчук С.Т., Петросян А.А. Забезпечення доступності до різн...
Evaluation of influence of factors of life-sustaining activity on the level from morbidity of leptospirosis in the example of the Chernivtsi region
The relevance of leptospirosis is associated with its wide spread in many countries of the world, an increase in the number of severe forms of the disease, often with a fatal outcome, which determines its high medical, s...
Memory roads
Memory roads
Reparation effects of vacuum wound therapy in patients with diabetic foot syndrome
Vacuum Therapy (Vacuum-assisted closure, VAC) - a method of complex therapy which is used to improve the healing of both acute chronic wounds in patients with diabetic foot syndrome. Due to widespread introduction of thi...